Chris Saris

Amgen (United States) — United States

Medicine · Health Sciences

19h-index3.8kcitations27works0.02yr avg
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Research Topics

Platelet Disorders and Treatments(4), Peptidase Inhibition and Analysis(3), Cancer Mechanisms and Therapy(3), T-cell and B-cell Immunology(2), Protein Kinase Regulation and GTPase Signaling(2)

Publications27 total

The WSX-1 pathway restrains intestinal T-cell immunity
International Immunology·2011· 10 citedOpen Access
Innate Resistance to Herpes simplex Virus is Genetically Complex
Investigative Ophthalmology & Visual Science·2004
Absence of an Essential Role for Thymic Stromal Lymphopoietin Receptor in Murine B-Cell Development
Molecular and Cellular Biology·2004· 150 citedOpen Access
Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)
Proceedings of the National Academy of Sciences·2003· 78 citedOpen Access
Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis
Journal of Cell Science·2002· 54 cited
Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity
Blood·2002· 174 citedOpen Access
WSX-1 Is Required for the Initiation of Th1 Responses and Resistance to L. major Infection
Immunity·2001· 408 citedOpen Access
Ectopic overexpression of c-mpl by retroviral-mediated gene transfer suppressed megakaryopoiesis but enhanced erythropoiesis in mice
Experimental Hematology·1999· 19 cited
Characterization of the Stat5 Protease
Journal of Biological Chemistry·1999· 46 citedOpen Access
Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5′ noncoding exons
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression·1996· 14 cited
Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice
Blood·1995· 157 citedOpen Access
Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoeitin/MGDF in megakaryocyte development
Cell·1995· 697 citedOpen Access
Interleukin-3 signals through multiple isoforms of Stat5.
The EMBO Journal·1995· 328 citedOpen Access
The tsA58 simian virus 40 large tumor antigen disrupts megakaryocyte differentiation in transgenic mice.
Proceedings of the National Academy of Sciences·1994· 11 citedOpen Access
Analysis of Pim-1 function in mutant mice.
PubMed·1993· 28 cited
The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG.
The EMBO Journal·1991· 302 citedOpen Access
Structure and chromosome assignment of the murine p36 calpactin I heavy chain gene
Biochemistry·1990· 33 cited
Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors
Cell·1989· 496 cited
Studies and methods related to murine leukemia virus
Data Archiving and Networked Services (DANS)·1988Open Access
cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I).
Journal of Biological Chemistry·1987· 91 citedOpen Access
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Frequent Co-authors

Brian F. Tack(5), Tony Hunter(5), Torsten Nygaard Kristensen(4), Henri P.J. Bloemers(4), Jos Domen(3), Anton Berns(3), Sharon Mu(3), Jet van Eenbergen(3), Todd Covey(2), Andrew Wakeham(2), Tak W. Mak(2), Min Xia(2), James N. Ihle(2), Christian Schindler(2), John R. Glenney(2), Robert A.J. Oostendorp(2), Kirsty N. Harvey(2), Nuray Kuşadasi(2), Rob E. Ploemacher(2), Elaine Dzierzak(2)