James W. Patrick

Chelsea and Westminster Hospital NHS Foundation Trust — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index4.9kcitations53works0.02yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(24), Ion channel regulation and function(11), Receptor Mechanisms and Signaling(10), Space Exploration and Technology(9), Cholinesterase and Neurodegenerative Diseases(6)

Publications53 total

Exploring the role of high-fidelity simulation for pre-foundation assistantship students to improve preparedness for practice
BMC Medical Education·2025Open Access
Failing to prepare is preparing to fail: the decline of life support training for medical trainees
BMJ·2023· 4 citedOpen Access
Exploring the efficacy and common themes of a pilot wellbeing intervention for final year medical students
Faculty of 1000 Research Ltd·2023Open Access
Tackling physician burnout: Too little, too late?
Canadian Medical Association Journal·2019Open Access
Hands‐on radiotherapy: Inspiring the next generation of <scp>STEM</scp> students
Journal of Applied Clinical Medical Physics·2019· 1 citedOpen Access
Piece of Mind
2003
Helicopter In-Flight Tracking System (HITS) for the Gulf of Mexico
AHS International Forum 58·2002· 1 cited
Increased Sensitivity to Nicotine-Induced Seizures in Mice Expressing the L250T α7 Nicotinic Acetylcholine Receptor Mutation
Molecular Pharmacology·2002· 5 cited
Increased Sensitivity to Nicotine-Induced Seizures in Mice Expressing the L250T α7 Nicotinic Acetylcholine Receptor Mutation
Molecular Pharmacology·2002· 71 cited
Normal apoptosis levels in mice expressing one α7 nicotinic receptor null and one L250T mutant allele
Neuroreport·2001· 13 cited
Altered baroreflex responses in α7 deficient mice
Behavioural Brain Research·2000· 67 cited
Excess “read-through” acetylcholinesterase attenuates but the “synaptic” variant intensifies neurodeterioration correlates
Proceedings of the National Academy of Sciences·2000· 130 citedOpen Access
Amino Acid Determinants of α7 Nicotinic Acetylcholine Receptor Surface Expression
Journal of Biological Chemistry·2000· 33 citedOpen Access
Mice Homozygous for the L250T Mutation in the α7 Nicotinic Acetylcholine Receptor Show Increased Neuronal Apoptosis and Die Within 1 Day of Birth
Journal of Neurochemistry·2000· 132 citedOpen Access
Multiorgan Autonomic Dysfunction in Mice Lacking the β2 and the β4 Subunits of Neuronal Nicotinic Acetylcholine Receptors
Journal of Neuroscience·1999· 283 citedOpen Access
Manipulations of ACHE gene expression suggest non-catalytic involvement of acetylcholinesterase in the functioning of mammalian photoreceptors but not in retinal degeneration
Molecular Brain Research·1999· 14 cited
Megacystis, mydriasis, and ion channel defect in mice lacking the α3 neuronal nicotinic acetylcholine receptor
Proceedings of the National Academy of Sciences·1999· 293 citedOpen Access
Distributions of nicotinic acetylcholine receptor α7 and β2 subunits on cultured hippocampal neurons
Neuroscience·1999· 111 cited
α7 Nicotinic Receptor Subunits Are Not Necessary for Hippocampal-Dependent Learning or Sensorimotor Gating: A Behavioral Characterization of <i>Acra7</i>-Deficient Mice
Learning & Memory·1998· 295 citedOpen Access
Contributions of N‐Linked Glycosylation to the Expression of a Functional α7‐Nicotinic Receptor in <i>Xenopus</i> Oocytes
Journal of Neurochemistry·1998· 64 citedOpen Access
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Frequent Co-authors

Avi Orr‐Urtreger(7), Mariella De Biasi(6), John A. Dani(6), Arthur L. Beaudet(6), Stephen F. Heinemann(5), Ron S. Broide(5), David Schubert(4), Finn M. Göldner(4), Jim Boulter(3), Richard Paylor(3), Lorna M. Colquhoun(3), Kelly T. Dineley(3), E. F. Kraly(3), Helgi Tarikas(2), John G. Connolly(2), Evan S. Deneris(2), David Goldman(2), Weiying Xu(2), Shari E. Gelber(2), Dawna Armstrong(2)