Darwin J. Prockop

Texas A&M Health Science Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

139h-index105.6kcitations686works0.02yr avg
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Research Topics

Connective tissue disorders research(165), Mesenchymal stem cell research(143), Collagen: Extraction and Characterization(96), Cell Adhesion Molecules Research(80), Protease and Inhibitor Mechanisms(61)

Publications685 total

Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain
International Journal of Molecular Sciences·2019· 104 citedOpen Access
Properties and Therapeutic Potentials of Adult Stem Cells from Bone Marrow Stroma (MSCs)
2019
STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation
Proceedings of the National Academy of Sciences·2019· 122 citedOpen Access
Absence of Therapeutic Benefit of the Anti-Inflammatory Protein TSG-6 for Corneal Alkali Injury in a Rat Model
Current Eye Research·2019· 7 cited
Intranasal Administration of MSC‐Derived Exosomes Modulate Status Epilepticus Induced Abnormal Plasticity of Newly Born Neurons and Microglial Activation in the Hippocampus
The FASEB Journal·2019
Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration
Proceedings of the National Academy of Sciences·2018· 126 citedOpen Access
In Vitro Macrophage Assay Predicts the In Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
Molecular Therapy — Methods & Clinical Development·2018· 77 citedOpen Access
Trastornos hereditarios del tejido conjuntivo
Dialnet (Universidad de la Rioja)·2018
Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner
Molecular Therapy·2017· 91 citedOpen Access
Data against a Common Assumption: Xenogeneic Mouse Models Can Be Used to Assay Suppression of Immunity by Human MSCs
Molecular Therapy·2017· 36 citedOpen Access
MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis
Stem Cell Reports·2017· 288 citedOpen Access
Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus
Proceedings of the National Academy of Sciences·2017· 395 citedOpen Access
Table of Contents
Cytotherapy·2016Open Access
TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury
Proceedings of the National Academy of Sciences·2016· 188 citedOpen Access
Comparison of the anti-inflammatory effects of induced pluripotent stem cell–derived and bone marrow–derived mesenchymal stromal cells in a murine model of corneal injury
Cytotherapy·2016· 70 cited
The exciting prospects of new therapies with mesenchymal stromal cells
Cytotherapy·2016· 127 citedOpen Access
Cancer cells enter dormancy after cannibalizing mesenchymal stem/stromal cells (MSCs)
Proceedings of the National Academy of Sciences·2016· 160 citedOpen Access
Stanniocalcin-1 attenuates ischemic cardiac injury and response of differentiating monocytes/macrophages to inflammatory stimuli
Translational research·2016· 32 citedOpen Access
Intraperitoneally infused human mesenchymal stem cells form aggregates with mouse immune cells and attach to peritoneal organs
Stem Cell Research & Therapy·2016· 87 citedOpen Access
Inflammation, fibrosis, and modulation of the process by mesenchymal stem/stromal cells
Matrix Biology·2016· 92 citedOpen Access
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Frequent Co-authors

Jeffrey L. Spees(6), Donald G. Phinney(5), Joni Ylöstalo(5), Kari I. Kivirikko(5), Alexandra Peister(5), Ryang Hwa Lee(4), Benjamin L. Larson(4), Edwin M. Horwitz(3), Gene Kopen(3), Carl A. Gregory(3), Scott D. Olson(3), David C. Colter(3), Reiner Class(3), Carla M. DiGirolamo(3), Jason R. Smith(3), Radhika Pochampally(3), Thomas J. Bartosh(3), Emily Schwarz(2), А. А Пулин(2), Min Jeong Seo(2)