J D Dasgupta

Tata Institute of Fundamental Research — India

Immunology and Microbiology · Life Sciences

13h-index1.9kcitations25works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(13), Immune Cell Function and Interaction(8), Immunotherapy and Immune Responses(7), Monoclonal and Polyclonal Antibodies Research(7), Glycosylation and Glycoproteins Research(4)

Publications25 total

Highlights from Kaleidoscope: A Discussion Meeting in Chemistry, Goa, India, July 2016
Chemical Communications·2017
Pillars Article: The CD4 Receptor Is Complexed in Detergent Lysates to a Protein-Tyrosine Kinase (Pp58) from Human T Lymphocytes. <i>Proc. Natl. Acad. Sci. USA</i> 1988. 85: 5190–5194
The Journal of Immunology·2010· 3 cited
Pillars article: the CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. 1988.
PubMed·2010· 10 citedOpen Access
CD4-independent signal transduction through the T-cell receptor (TCR/CD3).
PubMed·1994· 6 citedOpen Access
Protein kinase A-mediated phosphorylation of the T-cell surface antigen CD27.
PubMed·1993
Defective signal transduction via T-cell receptor-CD3 structure in T cells from rheumatoid arthritis patients
Human Immunology·1993· 22 cited
Phospholipase C-gamma 1 association with CD3 structure in T cells.
The Journal of Experimental Medicine·1992· 56 citedOpen Access
HLA-class I molecules regulate protein tyrosine kinase activity in T cells
Human Immunology·1991
PLC gamma 1, a possible mediator of T cell receptor function.
Journal of Biological Chemistry·1991· 71 citedOpen Access
Involvement of major histocompatibility complex class I antigens in T cell activation
European Journal of Immunology·1990· 27 cited
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.
Proceedings of the National Academy of Sciences·1989· 452 citedOpen Access
7.3-05 T cell-macrophage interaction via HLA class I antigens necessary for CD4+ T cell activation
Human Immunology·1989
3.1-02 HLA class I antigens on lymphocytes transduce signal by raising cytoplasmic calcium
Human Immunology·1989· 1 cited
Receptor-like nature of class I HLA: endocytosis via coated pits.
The Journal of Immunology·1988· 73 cited
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.
Proceedings of the National Academy of Sciences·1988· 719 citedOpen Access
Two variants of DRw52, DR3, and DQw2 specificities distinguish two different DR3-bearing extended haplotypes
Human Immunology·1988· 19 cited
Internalization of HLA molecules by macrophages/monocytes
Human Immunology·1988
Receptor-like role of HLA-class I antigens: regulation of T cell activation.
The Journal of Immunology·1987· 44 cited
The role of class I histocompatibility antigens in the regulation of T-cell activation.
Proceedings of the National Academy of Sciences·1987· 56 citedOpen Access
Stress, the Immune System, and Cancer
1986· 7 cited
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Frequent Co-authors

Valerie Relias(8), Stuart F. Schlossman(5), E J Yunis(5), Edmond J. Yunis(5), Christopher E. Rudd(4), James M. Trevillyan(4), Linda L. Wong(3), David L. Garbers(3), Henry S. Slayter(3), C. Granja(3), G. Swarup(2), Simon C. Watkins(2), Eduardo Egea(2), Antonio Iglesias(2), P Gladstone(2), Udai N. Singh(2), Elizabeth K. Barber(1), Li Li Lin(1), E.J. Yunis(1), Brian Druker(1)