Sharon L. Aukerman

Medicine · Health Sciences

27h-index3.0kcitations57works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(8), Fibroblast Growth Factor Research(7), Cancer Research and Treatments(7), Lymphoma Diagnosis and Treatment(6), Virus-based gene therapy research(6)

Publications57 total

HCD122, on human chronic lymphocytic leukemia cells The antileukemia activity of a human anti-CD40 antagonist antibody,
2013
Detection and Quantification of Cereblon Protein and mRNA in Multiple Myeloma Cell Lines and Primary CD138+multiple Myeloma Cells
Blood·2012· 7 cited
Pharmacokinetic Characterization of Amrubicin Cardiac Safety in an Ex Vivo Human Myocardial Strip Model. II. Amrubicin Shows Metabolic Advantages over Doxorubicin and Epirubicin
Journal of Pharmacology and Experimental Therapeutics·2012· 31 cited
Pharmacokinetic Characterization of Amrubicin Cardiac Safety in an Ex Vivo Human Myocardial Strip Model. I. Amrubicin Accumulates to a Lower Level than Doxorubicin or Epirubicin
Journal of Pharmacology and Experimental Therapeutics·2012· 10 cited
Increased cellular accumulation and distribution of amrubicin contribute to its activity in anthracycline-resistant cancer cells
Cancer Chemotherapy and Pharmacology·2011· 8 cited
Targeting the Wnt/β-Catenin Signaling Pathway and CD44-Mediated Adhesion As a Rational Approach to Overcome Lenalidomide Resistance in Multiple Myeloma
Blood·2011· 4 cited
Lenalidomide Induces Capping of CD20 and Cytoskeleton Proteins to Enhance Rituximab Immune Recognition of Malignant B-Cells
Blood·2010· 11 citedOpen Access
A Comparison of Azacitidine and Decitabine Activities in Acute Myeloid Leukemia Cell Lines
PLoS ONE·2010· 354 citedOpen Access
The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells
Blood·2008· 103 citedOpen Access
Recombinant Interleukin-2 Significantly Augments Activity of Rituximab in Human Tumor Xenograft Models of B-cell Non-Hodgkin Lymphoma
Journal of Immunotherapy·2006· 28 cited
HCD122, an Antagonist Human Anti-CD40 Monoclonal Antibody, Inhibits Tumor Growth in Xenograft Models of Human Diffuse Large B-Cell Lymphoma, a Subset of Non-Hodgkins Lymphoma.
Blood·2006· 7 cited
Efficacy of an Antagonistic Anti-CD40 Monoclonal Antibody, HCD122 (CHIR-12.12), in Preclinical Models of Human Non-Hodgkin’s Lymphoma and Hodgkin’s Disease.
Blood·2006· 9 cited
Novel Robust Hepatitis C Virus Mouse Efficacy Model
Antimicrobial Agents and Chemotherapy·2006· 35 citedOpen Access
A Non-Internalizing Anti-CD40 Antibody, CHIR-12.12, Blocks CD40L-Induced Cytokine Production and Mediates Greater ADCC Than Rituximab in Primary CLL Cells.
Blood·2005· 1 cited
Human Antagonistic Anti-CD40 Antibody, CHIR-12.12, Inhibits CD40-Mediated Survival of Chronic Lymphocytic Leukemia B Cells Leading to Cellular Apoptosis.
Blood·2005· 1 cited
Antagonist Anti-CD40 Antibody, CHIR-12.12, Induces ADCC, Inhibits Tumor Growth, and Prolongs Survival in a Human Multiple Myeloma Xenograft Model.
Blood·2005· 6 cited
CHIR-258: A Potent Inhibitor of FLT3 Kinase in Experimental Tumor Xenograft Models of Human Acute Myelogenous Leukemia
Clinical Cancer Research·2005· 111 citedOpen Access
<i>In vivo</i> Target Modulation and Biological Activity of CHIR-258, a Multitargeted Growth Factor Receptor Kinase Inhibitor, in Colon Cancer Models
Clinical Cancer Research·2005· 173 cited
beta-Catenin regulates vascular endothelial growth factor expression in colon cancer.
PubMed·2003· 274 cited
The pathogenesis of cancer metastasis: relevance to biotherapy
2003
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Frequent Co-authors

Glenn F. Pierce(9), Carla Heise(6), Evelyn N. Garrett(5), W Wiktor-Jędrzejczak(5), Barbara A. Sosnowski(5), Janet E. Price(4), Isaiah J. Fidler(4), Andrew Baird(4), Lois A. Chandler(4), Rajesh Chopra(4), Cheryl Goldbeck(3), Regina M. Housley(3), Helen Ye(3), Grazyna Ostrowska(3), Andrzej Wójtowicz(3), Marie A. Printz(3), Mohammad Luqman(3), Bahija Jallal(3), Montesa Patawaran(3), Sekhar Surapaneni(3)