Christine M. Gillen

Medicine · Health Sciences

24h-index2.5kcitations33works0.02yr avg
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Research Topics

Streptococcal Infections and Treatments(24), Antimicrobial Resistance in Staphylococcus(13), Neonatal and Maternal Infections(13), Infective Endocarditis Diagnosis and Management(5), Thermoregulation and physiological responses(4)

Publications33 total

All major cholesterol-dependent cytolysins use glycans as cellular receptors
Science Advances·2020· 67 citedOpen Access
A Controlled Human Infection Model of Group A <i>Streptococcus</i> Pharyngitis: Which Strain and Why?
mSphere·2019· 42 citedOpen Access
Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection
Scientific Reports·2017· 7 citedOpen Access
Streptococcus iniae cpsG alters capsular carbohydrate composition and is a cause of serotype switching in vaccinated fish
Veterinary Microbiology·2016· 9 cited
Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models
mBio·2016· 66 citedOpen Access
Known &lt;i&gt;S. pyogenes&lt;/i&gt; and SDSE collagen-binding M proteins harboring PARF.
Figshare·2015Open Access
Manganese Homeostasis in Group A Streptococcus Is Critical for Resistance to Oxidative Stress and Virulence
mBio·2015· 94 citedOpen Access
The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity
Proceedings of the National Academy of Sciences·2014· 114 citedOpen Access
Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus
Clinical Microbiology Reviews·2014· 889 citedOpen Access
An Antimicrobial Role for Zinc in Innate Immune Defense Against Group A Streptococcus
The Journal of Infectious Diseases·2014· 133 cited
The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication
Cell Host & Microbe·2013· 132 citedOpen Access
Streptococcal collagen‐like protein A and general stress protein 24 are immunomodulating virulence factors of group A <i>Streptococcus</i>
The FASEB Journal·2013· 12 citedOpen Access
Acquisition of the Sda1-Encoding Bacteriophage Does Not Enhance Virulence of the Serotype M1 Streptococcus pyogenes Strain SF370
Infection and Immunity·2013· 25 citedOpen Access
Streptokinase variants from <i><scp>S</scp>treptococcus pyogenes</i> isolates display altered plasminogen activation characteristics – implications for pathogenesis
Molecular Microbiology·2012· 42 citedOpen Access
Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone
The FASEB Journal·2012· 56 citedOpen Access
Molecular Characterization of the 2011 Hong Kong Scarlet Fever Outbreak
The Journal of Infectious Diseases·2012· 110 cited
Conserved anchorless surface proteins as group A streptococcal vaccine candidates
Journal of Molecular Medicine·2012· 61 citedOpen Access
Region Specific and Worldwide Distribution of Collagen-Binding M Proteins with PARF Motifs among Human Pathogenic Streptococcal Isolates
PLoS ONE·2012· 29 citedOpen Access
Group A Streptococcal Vaccine Candidates: Potential for the Development of a Human Vaccine
Current topics in microbiology and immunology·2012· 38 cited
Contribution of Plasminogen Activation towards the Pathogenic Potential of Oral Streptococci
PLoS ONE·2010· 32 citedOpen Access
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Frequent Co-authors

Mark J. Walker(21), Victor Nizet(10), Jason N. Cole(6), Anna Henningham(6), Gary W. Mack(6), E. R. Nadel(6), Gursharan S. Chhatwal(6), Timothy C. Barnett(5), Cheryl‐lynn Y. Ong(5), Mark R. Davies(5), Peter G. Maamary(4), Marcus Fulde(4), D. Patric Nitsche-Schmitz(4), Jason D. McArthur(3), Martina Sanderson‐Smith(3), Akira Takamata(3), Amanda J. Cork(3), Manfred Rohde(3), Nouri L. Ben Zakour(3), Scott A. Beatson(3)