HyeonJoo Cheon

Wayne State University — United States

Medicine · Health Sciences

17h-index2.7kcitations24works0.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(17), interferon and immune responses(15), Immune Cell Function and Interaction(4), Cancer-related molecular mechanisms research(3), NF-κB Signaling Pathways(3)

Publications24 total

How cancer cells make and respond to interferon-I
Trends in cancer·2022· 204 citedOpen Access
The JAK-STAT pathway at 30: Much learned, much more to do
Cell·2022· 597 citedOpen Access
PD-L1 sustains chronic, cancer cell–intrinsic responses to type I interferon, enhancing resistance to DNA damage
Proceedings of the National Academy of Sciences·2021· 61 citedOpen Access
Suppressing <scp>PAR</scp> ylation by 2′,5′‐oligoadenylate synthetase 1 inhibits <scp>DNA</scp> damage‐induced cell death
The EMBO Journal·2020· 5 citedOpen Access
Suppressing <scp>PAR</scp> ylation by 2′,5′‐oligoadenylate synthetase 1 inhibits <scp>DNA</scp> damage‐induced cell death
The EMBO Journal·2020· 27 citedOpen Access
Abstract 2884: Interferon Beta (IFN-B) re-activates canonical type I IFN signaling to differentiate breast cancer stem cells (CSCs) and suppress mesenchymal/CSC driven tumor recurrence
Cancer Research·2017· 1 cited
Responses to Cytokines and Interferons that Depend upon JAKs and STATs
Cold Spring Harbor Perspectives in Biology·2017· 104 citedOpen Access
Response to interferons and antibacterial innate immunity in the absence of tyrosine‐phosphorylated <scp>STAT</scp> 1
EMBO Reports·2016· 56 citedOpen Access
Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness
Proceedings of the National Academy of Sciences·2015· 88 citedOpen Access
Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex
Cell Reports·2015· 66 citedOpen Access
Abstract 485: Chronic exposure to a low dose of interferon-β increases levels of DNA damage resistance signature genes through unphosphorylated ISGF3
Cancer Research·2014· 1 cited
Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs
International Journal of Cancer·2014· 36 citedOpen Access
Interferons and Their Stimulated Genes in the Tumor Microenvironment
Seminars in Oncology·2014· 256 citedOpen Access
Concerted recruitment of the mediator complex explains STAT-NFkB interaction in the antimicrobial response of macrophages
2014
STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor
Proceedings of the National Academy of Sciences·2013· 321 citedOpen Access
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
The EMBO Journal·2013· 328 citedOpen Access
44
Cytokine·2013· 1 cited
CS07-5. Loss of p53 increases unphosphorylated STAT1, which induces resistance to DNA damage in cancer cells
Cytokine·2011
The Functions of Signal Transducers and Activators of Transcriptions 1 and 3 as Cytokine-Inducible Proteins
Journal of Interferon & Cytokine Research·2010· 135 citedOpen Access
PL2-4 Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes
Cytokine·2010
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Frequent Co-authors

George R. Stark(20), Elise Holvey-Bates(9), Yuxin Wang(4), Mark W. Jackson(4), Damian J. Junk(3), Priyank Shukla(3), Andrea Majoros(3), Claus Vogl(3), Jinbo Yang(2), Sebastian Wienerroither(2), Matthias Farlik(2), Bernadette Stych(2), Birgit Strobl(2), Mathias Müller(2), Thomas Decker(2), Anna A. Kondratova(2), Beihua Dong(2), Metis Hasipek(2), Irina Taran(2), Christina Gaughan(2)