Jean‐Pierre Hachem

Centre Hospitalier de Luxembourg — LU

Medicine · Health Sciences

24h-index3.4kcitations37works0.02yr avg
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Research Topics

Dermatology and Skin Diseases(18), Advancements in Transdermal Drug Delivery(16), Contact Dermatitis and Allergies(8), Skin and Cellular Biology Research(6), Ocular Surface and Contact Lens(5)

Publications37 total

Practical Use and Significance of Transepidermal Water Loss Measurements
2020· 2 cited
Shwachman–Diamond syndrome presenting with early ichthyosis, associated dermal and epidermal intracellular lipid droplets, hypoglycemia, and later distinctive clinical SDS phenotype
American Journal of Medical Genetics Part A·2016· 8 cited
Caspase-14-Deficient Mice Are More Prone to the Development of Parakeratosis
Journal of Investigative Dermatology·2012· 43 citedOpen Access
Cannabinoid receptors 1 and 2 oppositely regulate epidermal permeability barrier status and differentiation
Experimental Dermatology·2012· 48 cited
Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure and Function
American Journal Of Pathology·2011· 234 citedOpen Access
Skin physiology in neonates and young children of different age groups compared to adults: A randomized study
VUBIR (Vrije Universiteit Brussel)·2011
Filaggrin-induced stratum corneum pH modulation following external and internal stressors
VUBIR (Vrije Universiteit Brussel)·2011
Functional skin adaptation in infancy – almost complete but not fully competent
Experimental Dermatology·2010· 175 citedOpen Access
Lipid Rafts and Caveolae in the Terminal Differentiation of Epidermal Keratinocytes
The Open Dermatology Journal·2009· 1 citedOpen Access
Acute Acidification of Stratum Corneum Membrane Domains Using Polyhydroxyl Acids Improves Lipid Processing and Inhibits Degradation of Corneodesmosomes
Journal of Investigative Dermatology·2009· 127 citedOpen Access
The Keys to Epidermal Differentiation
Basic and clinical dermatology·2009· 1 cited
pH-Regulated Mechanisms Account for Pigment-Type Differences in Epidermal Barrier Function
Journal of Investigative Dermatology·2009· 155 citedOpen Access
The “Caveolae Brake Hypothesis” and the Epidermal Barrier
Journal of Investigative Dermatology·2008· 29 citedOpen Access
Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea
Contact Dermatitis·2008· 2 citedOpen Access
Topical Peroxisome Proliferator Activated Receptor Activators Accelerate Postnatal Stratum Corneum Acidification
Journal of Investigative Dermatology·2008· 38 citedOpen Access
Proteolytically Active Allergens Cause Barrier Breakdown
Journal of Investigative Dermatology·2008· 54 cited
Acute Modulations in Permeability Barrier Function Regulate Epidermal Cornification
American Journal Of Pathology·2007· 125 citedOpen Access
Daily treatment with adapalene gel 0.1% maintains initial improvement of acne vulgaris previously treated with oral lymecycline.
PubMed·2007· 37 cited
Caspase-14 protects against epidermal UVB photodamage and water loss
Nature Cell Biology·2007· 293 cited
Serine Protease Signaling of Epidermal Permeability Barrier Homeostasis
Journal of Investigative Dermatology·2006· 208 citedOpen Access
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Frequent Co-authors

Peter M. Elias(17), Diane Roseeuw(17), Debra Crumrine(15), Kenneth R. Feingold(15), Vera Rogiers(10), Truus Roelandt(10), Joachim W. Fluhr(9), Kristien De Paépe(9), Günter Burg(8), Renato G. Panizzon(7), Mao‐Qiang Man(6), Theodora M. Mauro(6), Leonard Kaufman(6), Barbara E. Brown(5), Matthias Schmuth(5), Christina Giddelo(5), Els Vanpée(5), Yoshikazu Uchida(4), Geertrui Denecker(4), Wim Declercq(4)