A M Skalka

Brigham and Women's Hospital — United States

Agricultural and Biological Sciences · Life Sciences

35h-index4.2kcitations69works0.02yr avg
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Research Topics

Plant Virus Research Studies(16), Bacteriophages and microbial interactions(16), HIV Research and Treatment(14), DNA and Nucleic Acid Chemistry(14), RNA and protein synthesis mechanisms(13)

Publications69 total

Issue Information
The FASEB Journal·2020Open Access
Principles of Virology, Volume 2: Pathogenesis and Control
2015· 18 cited
Principles of virology, Volume 1: molecular biology.
2008· 4 cited
Retroviral DNA integration and the DNA damage response
Cell Death and Differentiation·2005· 119 citedOpen Access
Characterization of a Naphthalene Derivative Inhibitor of Retroviral Integrases
AIDS Research and Human Retroviruses·2004· 6 cited
ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM HEPES
1999
ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM AMMONIUM SULFATE
1999
Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases
Journal of Virology·1997· 57 citedOpen Access
Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase
Journal of Virology·1996· 114 citedOpen Access
Concerted integration of linear retroviral DNA by the avian sarcoma virus integrase in vitro: dependence on both long terminal repeat termini
Journal of Virology·1996· 86 citedOpen Access
Enhanced and coordinated processing of synapsed viral DNA ends by retroviral integrases in vitro.
Genes & Development·1995· 42 citedOpen Access
Monoclonal antibodies against Rous sarcoma virus integrase protein exert differential effects on integrase function in vitro
Journal of Virology·1995· 6 citedOpen Access
Identification of Amino Acid Residues of the Retroviral Aspartic Proteinases Important for Substrate Specificity and Catalytic Efficiency
Advances in experimental medicine and biology·1995· 2 cited
Biochemical and physical studies of a retroviral protease
1994
Rapid solution assays for retroviral integration reactions and their use in kinetic analyses of wild-type and mutant Rous sarcoma virus integrases.
Proceedings of the National Academy of Sciences·1993· 26 citedOpen Access
Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases.
Molecular and Cellular Biology·1992· 548 citedOpen Access
Analysis of substrate interactions of the Rous sarcoma virus wild type and mutant proteases and human immunodeficiency virus-1 protease using a set of systematically altered peptide substrates.
Journal of Biological Chemistry·1992· 50 citedOpen Access
Processing of avian retroviral gag polyprotein precursors is blocked by a mutation at the NC-PR cleavage site
Journal of Virology·1992· 24 citedOpen Access
Assembly and processing of avian retroviral gag polyproteins containing linked protease dimers
Journal of Virology·1991· 43 citedOpen Access
A range of catalytic efficiencies with avian retroviral protease subunits genetically linked to form single polypeptide chains.
Journal of Biological Chemistry·1991· 38 citedOpen Access
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Frequent Co-authors

Jonathan Leis(12), Richard A. Katz(9), D Bizub(5), Moshe Kotler(5), Lynn W. Enquist(4), G Ju(4), Kathryn S. Jones(3), Waleed Danho(3), David Cobrinik(3), D A Soltis(3), Haim Burstein(3), Joseph Kulkosky(2), Michael Katzman(2), Mohindar S. Poonian(2), Robert Terry(2), George Kukolj(2), Geoffrey M. Duyk(2), Mathew Longiaru(2), Hidesaburô Hanafusa(2), Craig E. Cameron(2)