H.‐K. Heim

Federal Institute for Drugs and Medical Devices — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index178citations17works0.02yr avg
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Research Topics

Glycosylation and Glycoproteins Research(4), Proteoglycans and glycosaminoglycans research(4), Polyamine Metabolism and Applications(4), Helicobacter pylori-related gastroenterology studies(3), Neuropeptides and Animal Physiology(3)

Publications17 total

WHO informal consultation on revision of guidelines on evaluation of similar biotherapeutic products, virtual meeting, 30 June – 2 July 2021
Biologicals·2022· 4 citedOpen Access
Synthetic gestagens exert differential effects on arterial thrombosis and aortic gene expression in ovariectomized apolipoprotein <scp>E</scp>‐deficient mice
British Journal of Pharmacology·2014· 7 citedOpen Access
P359 LENTIVIRAL OVEREXPRESSION OF HYALURONIC ACID SYNTHASES 1 AND 2 RESTORES ESTRADIOL-MEDIATED INHIBITION OF PDGF-INDUCED PROLIFERATION IN VASCULAR SMOOTH MUSCLE CELLS
Atherosclerosis Supplements·2010· 1 cited
Effects of PGE2 and of different synthetic PGE derivatives on the glycosylation of pig gastric mucins
Prostaglandins Leukotrienes and Essential Fatty Acids·1998· 1 cited
Effects of PGE2 on amount and composition of high molecular weight glycoproteins released by human gastric mucous cells in primary culture
Prostaglandins Leukotrienes and Essential Fatty Acids·1997· 9 cited
Prostaglandin E2 alters terminal glycosylation of high molecular weight glycoproteins, released by pig gastric mucous cells in vitro
Prostaglandins Leukotrienes and Essential Fatty Acids·1995· 13 cited
Recovery of CCK response in gastric chief cell culture
Gastroenterology·1995
Effects of prostaglandins on [Ca2+]i and adenylate cyclase activity in isolated porcine gastric mucous cells.
PubMed·1994· 1 cited
Contents, Vol. 49, 1994
Pharmacology·1994Open Access
Eefects of EP-receptor subtype specific agonists and other prostanoids on adenylate cyclase activity of duodenal epithelial cells
Prostaglandins·1992· 35 cited
Effects of histamine and activators of the cyclic AMP system on protein synthesis in and release of high molecular weight glycoproteins from isolated gastric non‐parietal cells
British Journal of Pharmacology·1991· 8 citedOpen Access
Effects of PGE<sub>2</sub>, carbenoxolone, cholecystokinin, and the thromboxane‐mimetic u46619 on protein and glycoprotein production by isolated pig gastric mucosal cells
Alimentary Pharmacology & Therapeutics·1990· 7 cited
Stimulation of glycoprotein and protein synthesis in isolated pig gastric mucosal cells by prostaglandins.
Gut·1990· 14 citedOpen Access
Effects of Histamine on Protein and Glycoprotein Production of Isolated Pig Gastric Mucosal Cells
Pharmacology·1990· 24 cited
A calmodulin antagonist inhibits histamine-stimulated acid production by isolated rat parietal cells
Regulatory Peptides·1987· 11 cited
Cyclic GMP and acid production in isolated gastric cells of the rat
Naunyn-Schmiedeberg s Archives of Pharmacology·1985· 8 cited
Comparison of the effect of PGE2 and somatostatin on histamine stimulated14C-aminopyrine uptake and cyclic AMP formation in isolated rat gastric mucosal cells
Inflammation Research·1983· 35 cited

Frequent Co-authors

K.‐Fr. Sewing(8), A. Oestmann(4), H. -J. Ruoff(3), M.‐L. Enss(3), Winfried Beil(3), Wolfgang Schepp(2), U. Schmidt-Wittig(2), Hans J. Hedrich(2), K.‐Fr. Sewing(2), Till Freudenberger(2), Meenu Wadhwa(2), Hye‐Na Kang(2), Robin Thorpe(2), Ivana Knežević(2), Va Richmond(2), R. Reimer(1), R. Muallem(1), H.S. Odes(1), Julian Schneider(1), V. Schusdziarra(1)