DJ Back

University of Liverpool — United Kingdom

Medicine · Health Sciences

24h-index1.8kcitations58works0.02yr avg
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Research Topics

HIV/AIDS drug development and treatment(28), Pharmacological Effects and Toxicity Studies(15), Pharmacogenetics and Drug Metabolism(12), HIV/AIDS Research and Interventions(10), HIV Research and Treatment(8)

Publications58 total

The Effect of Gene Variants on Levonorgestrel Pharmacokinetics When Combined With Antiretroviral Therapy Containing Efavirenz or Nevirapine
Clinical Pharmacology & Therapeutics·2017· 30 citedOpen Access
A Call for a Consortium for Optimal Management of Drug–Drug Interactions in Patient Care
Clinical Pharmacology & Therapeutics·2017· 6 cited
Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy
HIV Medicine·2014· 12 cited
The use of a darunavir/ritonavir once‐daily regimen in two pregnant women
Journal of the International AIDS Society·2010Open Access
Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100, 200/150, and 200/50 mg twice daily in HIV‐negative volunteers
Journal of the International AIDS Society·2010· 1 citedOpen Access
The pharmacokinetic and safety profile of raltegravir and ribavirin, when dosed separately and together, in healthy volunteers
Journal of the International AIDS Society·2010· 4 citedOpen Access
SLCO3A1 expression is a major determinant of atazanavir PBMC penetration in HIV-infected patients
Journal of the International AIDS Society·2010· 1 citedOpen Access
Therapeutic drug monitoring (TDM) of atazanavir in pregnancy
Journal of the International AIDS Society·2010· 3 citedOpen Access
Population pharmacokinetic modelling of once‐daily ritonavir‐boosted darunavir in HIV‐infected patients
Journal of the International AIDS Society·2010· 8 citedOpen Access
Evaluating pharmacist involvement in HIV outpatient clinics: can medication histories, drug interaction checks and adherence assessments add benefit?
Journal of the International AIDS Society·2010· 2 citedOpen Access
HIV therapy in an ageing population — the challenge of polypharmacy
Journal of the International AIDS Society·2010· 1 citedOpen Access
Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy
HIV Medicine·2010· 37 citedOpen Access
The Relationships of ABCB1 3435C>T and CYP2B6 516G>T With High-Density Lipoprotein Cholesterol in HIV-Infected Patients Receiving Efavirenz
Clinical Pharmacology & Therapeutics·2009· 14 cited
Cytochrome P450 2B6 516G→T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population
HIV Medicine·2009· 69 citedOpen Access
The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC
British Journal of Pharmacology·2009· 73 citedOpen Access
A population pharmacokinetic model confirms an association between a pregnane-X-receptor (PXR) polymorphism and unboosted atazanavir clearance
2009
Plasma concentrations of boosted and unboosted atazanavir are predicted by 63396C>T SNP in the PXR gene
Journal of the International AIDS Society·2008Open Access
O122 Prevalence of drug interactions between antiretroviral and co-administered drugs at the Moi teaching and referral hospital (Ampath), Eldoret, Kenya
Journal of the International AIDS Society·2008· 6 citedOpen Access
An open-label multicentre pilot study evaluating the pharmacokinetics (PK) of co-administered lopinavir (LPV) and nevirapine (NVP) in HIV+ adults
Journal of the International AIDS Society·2008Open Access
Lopinavir is a substrate for SLCO1A2 but 516A>C and 38T>C polymorphisms do not influence lopinavir plasma concentrations
Journal of the International AIDS Society·2008· 2 citedOpen Access
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Frequent Co-authors

AM Breckenridge(14), SH Khoo(12), Andrew Owen(8), M. Orme(7), ML Orme(6), M Bruce MacIver(6), P.H. Rowe(6), JF Tjia(5), HS Purba(5), LJ Else(4), Laura Dickinson(4), J. Tjia(3), TW Mahungu(3), JL Howe(3), Mark C. Bates(3), John S. Lambert(3), Valerie Jackson(3), M Brennan(3), Michael Barry(3), FE Crawford(3)