W. Timothy Jenkins

University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index2.5kcitations43works0.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(24), Nanoplatforms for cancer theranostics(9), Glioma Diagnosis and Treatment(7), Cancer Research and Treatments(5), MicroRNA in disease regulation(3)

Publications43 total

Improved Methods to Generate Spheroid Cultures from Tumor Cells, Tumor Cells & Fibroblasts or Tumor-Fragments: Microenvironment, Microvesicles and MiRNA
PLoS ONE·2015· 40 citedOpen Access
Microvesicles as a Biomarker for Tumor Progression versus Treatment Effect in Radiation/Temozolomide-Treated Glioblastoma Patients
Translational Oncology·2014· 52 citedOpen Access
Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells
Journal of Pharmaceutics·2013· 3 citedOpen Access
Mechanisms of blood flow and hypoxia production in rat 9L-epigastric tumors
Tumor Microenvironment and Therapy·2012· 26 citedOpen Access
Abstract 5004: <i>In vivo</i> profiling of hypoxic mRNA and miRNA expression in gliomas and head and neck tumors
Cancer Research·2011
<i>In Vivo</i> Profiling of Hypoxic Gene Expression in Gliomas Using the Hypoxia Marker EF5 and Laser-capture Microdissection
Cancer Research·2011· 52 citedOpen Access
The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study
Translational Oncology·2010· 41 citedOpen Access
Early detection of radiation therapy response in non‐Hodgkin's lymphoma xenografts by <i>in vivo</i><sup>1</sup>H magnetic resonance spectroscopy and imaging
NMR in Biomedicine·2010· 45 cited
The radiation response of cells from 9L gliosarcoma tumours is correlated with [F18]-EF5 uptake
International Journal of Radiation Biology·2009· 23 citedOpen Access
Imaging and Analytical Methods as Applied to the Evaluation of Vasculature and Hypoxia in Human Brain Tumors
Radiation Research·2008· 46 citedOpen Access
Selective Radioprotection of Normal Tissues with Cerium Oxide Nanoparticles
International Journal of Radiation Oncology*Biology*Physics·2008· 11 cited
190 Microenvironment of brain tumors: Hypoxia, proliferation and vasculature
Radiotherapy and Oncology·2006
EF5 binding and clinical outcome in human soft tissue sarcomas
International Journal of Radiation Oncology*Biology*Physics·2006· 57 cited
Hypoxia Is Important in the Biology and Aggression of Human Glial Brain Tumors
Clinical Cancer Research·2004· 365 cited
Comparative Measurements of Hypoxia in Human Brain Tumors Using Needle Electrodes and EF5 Binding
Cancer Research·2004· 222 cited
Cyclophosphamide treatment modifies tumor oxygenation and glycolytic rates of RIF-1 tumors: 13C magnetic resonance spectroscopy, Eppendorf electrode, and redox scanning.
PubMed·2003· 32 cited
Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5
European Journal of Nuclear Medicine and Molecular Imaging·2003· 133 cited
Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion.
PubMed·2002· 32 cited
Effects of hyperglycemia on oxygenation, radiosensitivity and bioenergetic status of subcutaneous RIF-1 tumors
International Journal of Oncology·2002· 6 cited
Doppler ultrasound imaging detects changes in tumor perfusion during antivascular therapy associated with vascular anatomic alterations.
PubMed·2001· 110 cited
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Frequent Co-authors

Sydney M. Evans(29), Cameron J. Koch(19), Kevin W. Jenkins(9), Stephen M. Hahn(7), Edith M. Lord(5), C. J. Koch(5), Kevin Judy(4), Raymond E. Meyn(4), Harish Poptani(4), Wei‐Ting Hwang(3), Robert A. Lustig(3), Craig W. Stevens(3), Alexander R. Judkins(3), Paul J. Zhang(3), David F. Wilson(3), Alexander V. Kachur(3), Joel S. Karp(3), William R. Dolbier(3), Christian Koch(3), Kristine M. Laughlin(3)