Anna Spada

University of Milan — Italy

Medicine · Health Sciences

54h-index10.5kcitations294works0.02yr avg
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Research Topics

Pituitary Gland Disorders and Treatments(118), Growth Hormone and Insulin-like Growth Factors(78), Neuroendocrine Tumor Research Advances(47), Adrenal and Paraganglionic Tumors(38), Genetic Syndromes and Imprinting(32)

Publications291 total

Expression of Concern: Specific roles of Gi protein family members revealed by dissecting SST5 coupling in human pituitary cells
Journal of Cell Science·2022Open Access
DRD2 Agonist Cabergoline Abolished the Escape Mechanism Induced by mTOR Inhibitor Everolimus in Tumoral Pituitary Cells
Frontiers in Endocrinology·2022· 11 citedOpen Access
P720R USP8 Mutation Is Associated with a Better Responsiveness to Pasireotide in ACTH-Secreting PitNETs
Cancers·2022· 19 citedOpen Access
Impact of USP8 mutations on corticotroph tumor cells responsiveness to pasireotide
Endocrine Abstracts·2022
The positive feedback exerted by mtor inhibitor everolimus in pituitary neuroendocrine tumoral cells is reverted by cabergoline co-treatment
Endocrine Abstracts·2022
Genetic Profiling of a Cohort of Italian Patients with ACTH-Secreting Pituitary Tumors and Characterization of a Novel USP8 Gene Variant
Cancers·2021· 24 citedOpen Access
Drug resistance in pituitary tumours: from cell membrane to intracellular signalling
Nature Reviews Endocrinology·2021· 22 cited
USP8 inhibitor RA-9 reduces ACTH release and cell growth in tumor corticotrophs
Endocrine Related Cancer·2021· 25 cited
Novel insight into ACTH-secreting pituitary tumors biological behavior: hormone secretion and cell proliferation modulation by Ubiquitin Specific Peptidase 8 inhibitor RA-9
Endocrine Abstracts·2021
Genetic profiling of a cohort of Italian patients with ACTH-secreting pituitary tumors and characterization of a novel USP8 gene variant
Endocrine Abstracts·2021· 10 cited
A Novel Mechanism Regulating Dopamine Receptor Type 2 Signal Transduction in Pituitary Tumoral Cells: The Role of cAMP/PKA-Induced Filamin A Phosphorylation
Frontiers in Endocrinology·2021· 13 citedOpen Access
Pituitary Tumors: Genetic and Molecular Factors Underlying Pathogenesis and Clinical Behavior
Neuroendocrinology·2021· 38 citedOpen Access
Filamin A is required for somatostatin receptor type 5 expression and pasireotide-mediated signaling in pituitary corticotroph tumor cells
Molecular and Cellular Endocrinology·2021· 13 cited
Metformin and everolimus: A promising combination for neuroendocrine tumors treatment
Endocrine Abstracts·2020· 6 cited
A novel mechanism regulating dopamine receptor type 2 (DRD2) signal transduction in PRL- and ACTH-secreting pituitary tumoral cells: The role of cAMP/PKA-induced filamin A (FLNA) phosphorylation in the control of responsiveness to DRD2 agonist
Endocrine Abstracts·2020
Octreotide and pasireotide effects on medullary thyroid carcinoma (MTC) cells growth, migration and invasion
Endocrine Abstracts·2020· 2 cited
Metformin and Everolimus: A Promising Combination for Neuroendocrine Tumors Treatment
Cancers·2020· 24 citedOpen Access
Beta-Arrestin 2 Is Required for Dopamine Receptor Type 2 Inhibitory Effects on AKT Phosphorylation and Cell Proliferation in Pituitary Tumors
Neuroendocrinology·2020· 18 cited
SUN-213 The Role of Filamin A (FLNA) in the Regulation of Insulin-Like Growth Factor System in Adrenocortical Carcinomas
Journal of the Endocrine Society·2020Open Access
SAT-312 Beta-Arrestin 2 Is Required for Dopamine Receptor Type 2 Inhibitory Effects on Akt Phosphorylation and Cell Proliferation in Pituitary Tumors
Journal of the Endocrine Society·2020· 1 citedOpen Access
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Frequent Co-authors

Paolo Beck‐Peccoz(26), Giovanna Mantovani(24), Andrea Lania(19), Sabrina Corbetta(10), Maura Arosio(9), G. Faglia(9), Emanuele Ferrante(7), Erika Peverelli(7), Luca Persani(6), Francesca Marta Elli(6), G. Giannattasio(6), Cristina L. Ronchi(5), M. Bassetti(5), Alfredo Scillitani(5), Lucia Vallar(4), Sara Bondioni(4), Marco Locatelli(4), Claudia Giavoli(4), Luisa De Sanctis(4), Paola Loli(3)