Jean‐Pierre Changeux

Institut Pasteur — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index8.3kcitations43works2.82yr avg
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Research Topics

Nicotinic Acetylcholine Receptors Study(24), Receptor Mechanisms and Signaling(16), Ion channel regulation and function(7), Neuroscience and Neuropharmacology Research(6), Neural dynamics and brain function(5)

Publications43 total

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases
Universität Zürich, ZORA·2025Open Access
GNW theoretical framework and the ‘Adversarial testing of global neuronal workspace and integrated information theories of consciousness’
2025Open Access
La poétique dans le cerveau
Collège de France eBooks·2025Open Access
GNW theoretical framework and the “adversarial testing of global neuronal workspace and integrated information theories of consciousness”
Neuroscience of Consciousness·2025· 4 citedOpen Access
Consciousness : from molecular to social scales
2024Open Access
Is artificial consciousness achievable? Lessons from the human brain
Neural Networks·2024· 13 citedOpen Access
A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications
Comptes Rendus Biologies·2020· 304 citedOpen Access
Conscious Processing and the Global Neuronal Workspace Hypothesis
Neuron·2020· 1.0k citedOpen Access
Allostery in Its Many Disguises: From Theory to Applications
Structure·2019· 389 citedOpen Access
Nicotine reverses hypofrontality in animal models of addiction and schizophrenia
Nature Medicine·2017· 180 citedOpen Access
Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation
Cell·2016· 329 citedOpen Access
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors
Science Translational Medicine·2015· 111 citedOpen Access
International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands
Pharmacological Reviews·2014· 234 citedOpen Access
Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine
Proceedings of the National Academy of Sciences·2011· 152 cited
α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6β4 and α6β2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release
The FASEB Journal·2010· 74 citedOpen Access
α7 Nicotinic Acetylcholine Receptor Regulates Airway Epithelium Differentiation by Controlling Basal Cell Proliferation
American Journal Of Pathology·2009· 82 citedOpen Access
Regional changes in the cholinergic system in mice lacking monoamine oxidase A
Brain Research Bulletin·2008· 13 cited
Regional differential effects of chronic nicotine on brain α4-containing and α6-containing receptors
Neuroreport·2008· 14 cited
Intracellular complexes of the β2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics
Proceedings of the National Academy of Sciences·2007· 64 citedOpen Access
Conscious, preconscious, and subliminal processing: a testable taxonomy
Trends in Cognitive Sciences·2006· 2.0k cited
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Frequent Co-authors

Nicolas Le Novère(4), Uwe Maskos(4), Isabelle Cloëz-Tayarani(4), Stanislas Dehaene(3), Lionel Naccache(3), Claire Sergent(3), Clément Léna(3), Francesco Rossi(3), J. Michael McIntosh(3), Monique Huchet(3), Anne Devillers‐Thiéry(3), Michele Farisco(3), Allan C. Collins(2), Sharon R. Grady(2), Jon Lindstrom(2), Michèle Zoli(2), Arthur Christopoulos(2), Jerry A. Stitzel(2), Marcelo J. Villar(2), Michèle Roa(2)