Lauren M. Cagen

University of Tennessee Health Science Center — United States

Medicine · Health Sciences

22h-index2.2kcitations54works0.02yr avg
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Research Topics

Inflammatory mediators and NSAID effects(19), Cholesterol and Lipid Metabolism(14), Eicosanoids and Hypertension Pharmacology(13), Peroxisome Proliferator-Activated Receptors(8), Liver Disease Diagnosis and Treatment(7)

Publications54 total

Insulin Enhances Posttranslational Processing of Nascent SREBP‐1c by Promoting its Phosphorylation and Association with COPII vesicles
The FASEB Journal·2009· 11 cited
Hepatic Gene Expression in Morbidly Obese Women: Implications for Disease Susceptibility
Obesity·2009· 39 cited
Insulin Enhances Post-translational Processing of Nascent SREBP-1c by Promoting Its Phosphorylation and Association with COPII Vesicles
Journal of Biological Chemistry·2009· 131 citedOpen Access
Expression of the Rat Sterol Regulatory Element-binding Protein-1c Gene in Response to Insulin Is Mediated by Increased Transactivating Capacity of Specificity Protein 1 (Sp1)
Journal of Biological Chemistry·2007· 55 citedOpen Access
Insulin stimulates processing of SREBP‐1 but not SREBP‐2 in rat hepatocytes
The FASEB Journal·2006
40 MICROARRAY ANALYSIS OF HEPATIC GENE EXPRESSION IN OBESE HUMANS UNDERGOING BARIATRIC SURGERY.
Journal of Investigative Medicine·2006
Posttranslational processing of SREBP-1 in rat hepatocytes is regulated by insulin and cAMP
Biochemical and Biophysical Research Communications·2005· 49 cited
Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y <i>cis</i>-acting elements
Biochemical Journal·2004· 139 citedOpen Access
Dietary Olive Oil and Menhaden Oil Mitigate Induction of Lipogenesis in Hyperinsulinemic Corpulent JCR:LA-cp Rats: Microarray Analysis of Lipid-Related Gene Expression
Endocrinology·2004· 45 citedOpen Access
43 IN CORPULENT JCR RATS, OLIVE OIL AND FISH OIL DIETS EFFECTIVELY MITIGATE THE EFFECT OF HYPERINSULINEMIA TO INDUCE SREBP-1 AND LIPOGENIC ENZYME GENE EXPRESSION.
Journal of Investigative Medicine·2004
Regulation of the Rat SREBP-1c Promoter in Primary Rat Hepatocytes
Biochemical and Biophysical Research Communications·2002· 111 cited
Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat
Journal of Lipid Research·2001· 63 citedOpen Access
Apolipoprotein B mRNA editing and apolipoprotein gene expression in the liver of hyperinsulinemic fatty zucker rats: Relationship to very low density lipoprotein composition
Lipids·1999· 8 cited
Insulin increases expression of apobec-1, the catalytic subunit of the apolipoprotein B mRNA editing complex in rat hepatocytes
Metabolism·1998· 21 cited
Diabetes and proteolysis: Effects on carnitine palmitoyltransferase‐I and malonyl‐CoA binding
Lipids·1995· 9 cited
Effects of Dietary Cholesterol on Hepatic Metabolism of Free Fatty Acid and Secretion of VLDL in the Hamster
Biochemical and Biophysical Research Communications·1994· 15 cited
Stimulation of fatty acid biosynthesis by dietary cholesterol and of cholesterol synthesis by dietary fatty acid.
Journal of Lipid Research·1994· 57 citedOpen Access
Biphasic effect of oleic acid on hepatic cholesterogenesis
Biochemical and Biophysical Research Communications·1992· 3 cited
Regulation of hepatic secretion of very low density lipoprotein by dietary cholesterol.
Journal of Lipid Research·1992· 119 citedOpen Access
Biphasic effect of oleic acid on hepatic cholesterol synthesis
FASEB Journal (Federation of American Societies for Experimental Biology); (United States)·1990
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Frequent Co-authors

Henry G. Wilcox(18), Marshall B. Elam(13), Xiong Deng(11), Rajendra Raghow(11), Murray Heimberg(10), Philip G. Baer(10), Edwards A. Park(8), Chandrahasa R. Yellaturu(6), John J. Pisano(4), Thomas V. Fungwe(4), Poonam Kumar(3), Herbert Friedmann(3), Alberto Nasjletti(3), Zahir Qureshi(3), Kafait U. Malik(2), James C. Russell(2), A. Erman(2), John Killmar(2), D. David Pifer(2), A Sheybani(2)