Maria Niewolna

Indiana University – Purdue University Indianapolis — United States

Medicine · Health Sciences

18h-index2.8kcitations39works0.02yr avg
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Research Topics

Bone health and treatments(17), Bone Metabolism and Diseases(13), TGF-β signaling in diseases(7), Multiple Myeloma Research and Treatments(5), Cancer, Hypoxia, and Metabolism(3)

Publications39 total

Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis
PMC·2017
Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis
Oncotarget·2017· 43 citedOpen Access
Excess TGF-β mediates muscle weakness associated with bone metastases in mice
2015
Excess TGF-β mediates muscle weakness associated with bone metastases in mice
Nature Medicine·2015· 367 citedOpen Access
TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis
BoneKEy Reports·2015· 18 cited
The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone
Cancer Cell·2015· 207 citedOpen Access
Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis
PMC·2014
Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis
Breast Cancer Research·2014· 44 citedOpen Access
Abstract 733: Effects of cabozantinib on breast cancer bone metastases, overall survival, and bone mass in a mouse model
Cancer Research·2014
osteoclast-stimulating activity 1-integrin enhances production of β 4 α VCAM-1 and cell contact between marrow stromal cells and myeloma cells via - Cell
2013· 1 cited
Halofuginone inhibits the establishment and progression of melanoma bone metastases
2012
Halofuginone Inhibits the Establishment and Progression of Melanoma Bone Metastases
Cancer Research·2012· 77 citedOpen Access
Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor
Journal of Bone and Mineral Research·2011· 35 citedOpen Access
Halofuginone reduces bone metastases: TGF-β-dependent and independent effects
Bone·2010
TGF-β-RI Kinase Inhibitor SD-208 Reduces the Development and Progression of Melanoma Bone Metastases
Cancer Research·2010· 217 citedOpen Access
Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
PLoS ONE·2009· 206 citedOpen Access
Pharmacologic Inhibition of the TGF-β Type I Receptor Kinase Has Anabolic and Anti-Catabolic Effects on Bone
PLoS ONE·2009· 178 citedOpen Access
P48. Transforming growth factor β receptor I kinase inhibitor and bisphosphonates are additive to reduce breast cancer bone metastases
Cancer Treatment Reviews·2008· 4 cited
The Effect of the Bisphosphonate Ibandronate on Breast Cancer Metastasis to Visceral Organs
Breast Cancer Research and Treatment·2002· 91 cited
A Bone-Seeking Clone Exhibits Different Biological Properties from the MDA-MB-231 Parental Human Breast Cancer Cells and a Brain-Seeking Clone In Vivo and In Vitro
Journal of Bone and Mineral Research·2001· 478 citedOpen Access
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Frequent Co-authors

Theresa A. Guise(15), Toshiyuki Yoneda(12), Khalid S. Mohammad(11), John M. Chirgwin(10), Paul J. Williams(9), Pierrick G.J. Fournier(9), Xiang Peng(8), Holly W. Davis(8), Gregory R. Mundy(8), Christopher R. McKenna(7), Patricia Juárez(6), Toshimi Michigami(6), Khalid S. Mohammad(6), Alain Mauviel(5), Ryan C. McKenna(5), Toru Hiraga(4), A Gola(4), Riko Nishimura(3), David L. Waning(3), Sutha K. John(3)