L Jacobs

Medicine · Health Sciences

13h-index641citations25works0.02yr avg
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Research Topics

Herpesvirus Infections and Treatments(13), Virus-based gene therapy research(8), Virology and Viral Diseases(7), Animal Virus Infections Studies(7), Animal Disease Management and Epidemiology(5)

Publications25 total

NOD2/CARD15 modulates specific Toll-like receptor pathways for the induction of cytokine release
European Journal of Gastroenterology & Hepatology·2005
Detection of carriers of foot-and-mouth disease virus among vaccinated cattle
Veterinary Microbiology·2004· 59 citedOpen Access
Characterization of changes in the short unique segment of pseudorabies virus BUK-TK900 (Suivac A) vaccine strain
Archives of Virology·2003· 4 citedOpen Access
A highly specific and sensitive sandwich blocking ELISA based on baculovirus expressed pseudorabies virus glycoprotein B
Journal of Virological Methods·2000· 14 cited
Detection of pseudorabies virus DNA in individual single-reactor pigs found in certified pseudorabies-free herds
Research in Veterinary Science·1999· 3 cited
The FMD-NS ELISA, the most sensitive test to detect FMDV infected animals in a vaccinated population
1998· 1 cited
Detection of wild-type Aujeszky's disease virus by polymerase chain reaction in sheep vaccinated with a modified live vaccine strain
Research in Veterinary Science·1997· 8 citedOpen Access
Pseudorabies virus infections in pigs : Role of viral proteins in virulence, pathogenesis and transmission
Socio-Environmental Systems Modeling·1997Open Access
Pseudorabies virus infections in pigs. Role of viral proteins in virulence, pathogenesis and transmission.
PubMed·1997· 41 cited
An indirect double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) using baculovirus-expressed antigen for the detection of antibodies to glycoprotein E of pseudorabies virus and comparison of the method with blocking ELISAs
Clinical and Diagnostic Laboratory Immunology·1996· 20 cited
Characterization of live pseudorabies virus vaccines.
PubMed·1995· 5 cited
Glycoprotein gE-negative Pseudorabies Virus has a Reduced Capability to Infect Second- and third-order Neurons of the Olfactory and Trigeminal Routes in the Porcine Central Nervous System
Journal of General Virology·1994· 75 cited
Glycoprotein E of pseudorabies virus and homologous proteins in otheralphaherpesvirinae
Archives of Virology·1994· 67 cited
Epitope-specific antibody response against glycoprotein E of pseudorabies virus
Clinical and Diagnostic Laboratory Immunology·1994· 22 citedOpen Access
Glycoprotein gI of pseudorabies virus: epitope-specific antibody response in mice and pigs.
PubMed·1994· 7 cited
Glycoprotein I of pseudorabies virus (Aujeszky's disease virus) determines virulence and facilitates penetration of the virus into the central nervous system of pigs.
PubMed·1994· 15 cited
Deleting two amino acids in glycoprotein gI of pseudorabies virus decreases virulence and neurotropism for pigs, but does not affect immunogenicity
Journal of General Virology·1993· 59 cited
Deleting valine-125 and cysteine-126 in glycoprotein gI of pseudorabies virus strain NIA-3 decreases plaque size and reduces virulence in mice
Archives of Virology·1993· 33 cited
Epitope analysis of glycoprotein I of pseudorabies virus
Journal of General Virology·1990· 33 cited
Synthesis of long cDNA from viral RNA template
Gene Analysis Techniques·1988· 7 citedOpen Access
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Frequent Co-authors

Tjeerd G. Kimman(7), W. A. M. Mulder(6), A. L. J. Gielkens(4), B A van der Zeijst(3), J.T. van Oirschot(3), M. C. Horzinek(2), Jan Priem(2), J. M. A. Pol(2), Ben Peeters(2), T.G. Kimman(2), Bogusław Szewczyk(2), Krystyna Bieńkowska-Szewczyk(2), Willy J. M. Spaan(1), G. L. Kok(1), F. Wagenaar(1), J. M. A. Pol(1), P. Moonen(1), Annelies Crienen(1), A. Dekker(1), E. Gruys(1)