Curtis W. Conroy

University of Florida — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index697citations24works0.02yr avg
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Research Topics

Enzyme function and inhibition(10), Electrochemical sensors and biosensors(4), Glaucoma and retinal disorders(4), Protein Interaction Studies and Fluorescence Analysis(4), Chemical Reactions and Mechanisms(4)

Publications24 total

Corneal Sequestration and Delivery to Ciliary Process of Six Topically Applied Sulfonamides
Journal of Ocular Pharmacology and Therapeutics·1999· 3 cited
The Ocular Distribution of Methazolamide After Corneal and Scleral Administration: The Effect of Ionization State
Journal of Ocular Pharmacology and Therapeutics·1998· 6 cited
Sulfonamides Do Not Reach the Retina in Therapeutic Amounts after Topical Application to the Cornea
Journal of Ocular Pharmacology and Therapeutics·1997· 13 cited
ChemInform Abstract: Carbonic Anhydrase Inhibitors: Synthesis and Inhibitory Properties of 1,3,4‐Thiadiazole‐2,5‐bissulfonamide.
ChemInform·1997
Is cyanate a carbonic anhydrase substracte?
Proteins Structure Function and Bioinformatics·1997· 52 cited
Ocular Absorption, Blood Levels, and Excretion of Dorzolamide, a Topically Active Carbonic Anhydrase Inhibitor
Journal of Ocular Pharmacology and Therapeutics·1997· 57 cited
Renal and Cerebrospinal Fluid Formation Pharmacology of a High Molecular Weight Carbonic Anhydrase Inhibitor
Journal of Pharmacology and Experimental Therapeutics·1997· 41 cited
Synthesis and Properties of Two New Membrane-Impermeant High-Molecular-Weight Carbonic Anhydrase Inhibitors
Bioorganic Chemistry·1996· 15 cited
Membrane Carbonic Anhydrase (IV) and Ciliary Epithelium. Carbonic Anhydrase Activity is Present in the Basolateral Membranes of the Non-pigmented Ciliary Epithelium of Rabbit Eyes
Experimental Eye Research·1996· 53 citedOpen Access
The effect of temperature on the binding of sulfonamides to carbonic anhydrase isoenzymes I, II, and IV.
Molecular Pharmacology·1995· 21 cited
Effect of pH on the ocular distribution of a topical carbonic anhydrase inhibitor
Experimental Eye Research·1995· 15 cited
A new class of carbonic anhydrase inhibitor.
Journal of Biological Chemistry·1993· 107 citedOpen Access
The microchemical detection of carbonic anhydrase in corneal epithelia
Experimental Eye Research·1992· 19 cited
Influence of Ion Pairing Salts on the Transcorneal Permeability of Ionized Sulfonamides
Journal of Ocular Pharmacology and Therapeutics·1992· 3 cited
Chemical and pharmacological properties of MK-927, a sulfonamide carbonic anhydrase inhibitor that lowers intraocular pressure by the topical route
Experimental Eye Research·1990· 56 cited
The permeability of hydrophobic membranes to 22Na salts and 14CO2 in low dielectric media
Biophysical Chemistry·1989· 2 cited
ChemInform Abstract: Synthesis and Physicochemical Properties of Thiadiazolo(3,2‐a)pyrimidinesulfonamides and Thiadiazolo(3,2‐a)triazinesulfonamides as Candidates for Topically Effective Carbonic Anhydrase Inhibitors.
ChemInform·1988
Synthesis and physicochemical properties of thiadiazolo[3,2-a]pyrimidinesulfonamides and thiadiazolo[3,2-a]triazinesulfonamides as candidates for topically effective carbonic anhydrase inhibitors
Journal of Medicinal Chemistry·1987· 41 cited
The determination of osteopetrotic phenotypes by selective inactivation of red cell carbonic anhydrase isoenzymes
Clinica Chimica Acta·1985· 14 cited
The nonenzymatic displacement of the sulfamoyl group from different classes of aromatic compounds by glutathione and cysteine.
Drug Metabolism and Disposition·1984· 33 cited
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Frequent Co-authors

Thomas H. Maren(12), T. H. Maren(6), James E. Erman(4), George C. Wynns(4), Amir Bar-Ilan(3), Claudiu T. Supuran(2), Alan R. Katritzky(2), Kenneth C. Caster(2), Paul D. Tyma(1), Peter H. Daum(1), Norman S. Levy(1), William F. Brechue(1), Hitoshi Matsui(1), Masakazu Murakami(1), Andrew F. Mead(1), Marvin L. Sears(1), D R Godman(1), Harvey Schwam(1), Bruce A. Lent(1), Richard Henry Buck(1)