Claude R. Benedict

Pennsylvania State University — United States

Medicine · Health Sciences

41h-index10.2kcitations137works2.52yr avg
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Research Topics

Heart Failure Treatment and Management(19), Cardiovascular Function and Risk Factors(19), Cardiac electrophysiology and arrhythmias(12), Nitric Oxide and Endothelin Effects(10), Antioxidant Activity and Oxidative Stress(10)

Publications137 total

Three-Dimensional Assessment of Charcot Neuroarthropathy Deformities: Comparison of Standard 2D vs Patient-Specific 3D Measurements
Foot & Ankle International·2025· 1 citedOpen Access
Rate of Osteoporosis Evaluation and Treatment Following Kyphoplasty in Patients With Vertebral Compression Fractures: A Retrospective Study and Review of the Literature
Geriatric Orthopaedic Surgery & Rehabilitation·2025· 4 citedOpen Access
Comparative neurohormonal responses in patients with preserved and impaired left ventricular ejection fraction: Results of the studies of left ventricular dysfunctions (SOLVD) registry
UNC Libraries·2021Open Access
Relation of neurohumoral activation to clinical variables and degree of ventricular dysfunction: A report from the registry of studies of left ventricular dysfunction
UNC Libraries·2021Open Access
Abstract 396: High Doses of a Novel Niacin Analog Are Devoid of Clinically Relevant Adverse Events in Safety Trials in Healthy Volunteers
Arteriosclerosis Thrombosis and Vascular Biology·2014
The high-fat high-fructose hamster as an animal model for niacin’s biological activities in humans
Metabolism·2013· 9 cited
Abstract 18285: ARI-3037MO, a Novel Niacin Analog, Significantly Improves Plasma Lipid Levels in the Hyperlipidemic Golden Syrian Hamster
Circulation·2011· 2 cited
Discovery, Engineering and Pre-Clinical Evaluation of an Anti-vWF A1 Domain Aptamer.
Blood·2006
Human Urotensin-II Potentiates the Mitogenic Effect of Mildly Oxidized Low-Density Lipoprotein on Vascular Smooth Muscle Cells: Comparison with Other Vasoactive Agents and Hydrogen Peroxide
Hypertension Research·2006· 28 citedOpen Access
Plasma norepinephrine predicts 12-year survival in patients with reduced ejection fractions from the studies of left ventricular dysfunction (SOLVD)
Journal of the American College of Cardiology·2003
Thrombolysis by excimer laser photoablation
2003· 6 cited
Induction of endothelial cell proliferation by angiogenic factors released by activated monocytes
Cardiovascular Radiation Medicine·2002· 52 cited
Synergistic effect of urotensin II with mildly oxidized LDL on vascular smooth muscle cell proliferation
Japanese Circulation Journal-english Edition·2002· 1 cited
Lysophosphatidylcholine is a major contributor to the synergistic effect of mildly oxidized low-density lipoprotein with endothelin-1 on vascular smooth muscle cell proliferation
Journal of the American College of Cardiology·2002· 1 cited
Lysophosphatidylcholine Is a Major Contributor to the Synergistic Effect of Mildly Oxidized Low-Density Lipoprotein With Endothelin-1 on Vascular Smooth Muscle Cell Proliferation
Journal of Cardiovascular Pharmacology·2002· 23 cited
Monocyte chemotactic protein 1 amplifies serotonin-induced vascular smooth muscle cell proliferation
Journal of the American College of Cardiology·2002· 1 cited
Antioxidant N-acetylcysteine inhibits vasoactive agents potentiated mitogenic effect of mildly oxidized low-density lipoprotein on vascular smooth muscle cells
Journal of the American College of Cardiology·2002· 1 cited
Antioxidant N-Acetylcysteine Inhibits Vasoactive Agents-Potentiated Mitogenic Effect of Mildly Oxidized LDL on Vascular Smooth Muscle Cells
Hypertension Research·2002· 9 citedOpen Access
Lysophosphatidylcholine Potentiates the Mitogenic Effect of Various Vasoactive Compounds on Rabbit Aortic Smooth Muscle Cells.
Japanese Heart Journal·2002· 14 citedOpen Access
Oxidized Low-Density Lipoproteins Potentiate the Mitogenic Effect of 5-Hydroxytryptamine on Vascular Smooth Muscle Cells.
Japanese Heart Journal·2002· 7 citedOpen Access
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Frequent Co-authors

Rajbabu Pakala(11), Salim Yusuf(7), Barry Greenberg(6), Takuya Watanabe(6), Takashi Katagiri(6), David E. Johnstone(5), Philip C. Kirlin(4), John M. Nicklas(4), Michel F. Rousseau(4), Miguel A. Quiñones(4), Brent J. Shelton(4), L. Maximilian Buja(4), James T. Willerson(4), William F. Hahne(4), Gary S. Francis(3), H. Pouleur(3), Martial G. Bourassa(3), Marvin A. Konstam(3), Pamela S. Douglas(3), Beverly H. Lorell(3)