Noriaki Ikemoto

Denso (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index6.9kcitations137works0.02yr avg
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Research Topics

Ion channel regulation and function(102), Cardiac electrophysiology and arrhythmias(62), Neuroscience and Neuropharmacology Research(16), Cardiomyopathy and Myosin Studies(13), Neuroscience and Neural Engineering(13)

Publications137 total

Distributed Route Optimization for Mixed Package-Passenger System Incorporating Ridesharing Passenger Matching
IFAC-PapersOnLine·2023· 1 citedOpen Access
Enhanced binding of calmodulin to the ryanodine receptor corrects contractile dysfunction in failing hearts
Cardiovascular Research·2012· 29 citedOpen Access
Mutation-Linked Defective Interdomain Interactions Within Ryanodine Receptor Cause Aberrant Ca <sup>2+</sup> Release Leading to Catecholaminergic Polymorphic Ventricular Tachycardia
Circulation·2011· 66 citedOpen Access
Aberrant interaction of calmodulin with the ryanodine receptor develops hypertrophy in the neonatal cardiomyocyte
Biochemical Journal·2011· 11 cited
Effects of Conformational Peptide Probe DP4 on Bidirectional Signaling between DHPR and RyR1 Calcium Channels in Voltage-Clamped Skeletal Muscle Fibers
Biophysical Journal·2011· 9 citedOpen Access
Intracellular translocation of calmodulin and Ca2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes
Biochemical and Biophysical Research Communications·2010· 16 citedOpen Access
Dynamic, inter-subunit interactions between the N-terminal and central mutation regions of cardiac ryanodine receptor
Journal of Cell Science·2010· 41 cited
Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca2+ release in heart failure
Cardiovascular Research·2010· 79 citedOpen Access
Catecholaminergic Polymorphic Ventricular Tachycardia Is Caused by Mutation-Linked Defective Conformational Regulation of the Ryanodine Receptor
Circulation Research·2010· 160 citedOpen Access
Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction
Biochemical and Biophysical Research Communications·2010· 82 cited
Effects of Domain Peptide DP4 on Depolarization-Induced Calcium Transients and Calcium Currents in Voltage-Clamped Fibers from Mouse FDB Skeletal Muscle
Biophysical Journal·2010Open Access
Dantrolene, a Therapeutic Agent for Malignant Hyperthermia, Markedly Improves the Function of Failing Cardiomyocytes by Stabilizing Interdomain Interactions Within the Ryanodine Receptor
Journal of the American College of Cardiology·2009· 187 citedOpen Access
Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle from Inclusion Body Myositis mice
Biophysical Journal·2009Open Access
Relocation of Calmodulin in Hypertrophic Neonatal Cardiomyocytes
Biophysical Journal·2009Open Access
Defective regulation of the ryanodine receptor induces hypertrophy in cardiomyocytes
Biochemical and Biophysical Research Communications·2009· 11 citedOpen Access
Alternative splicing of RyR1 alters the efficacy of skeletal EC coupling
Cell Calcium·2009· 57 citedOpen Access
Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle
Neurobiology of Aging·2008· 59 citedOpen Access
Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts
Cardiovascular Research·2008· 88 citedOpen Access
Interaction of the Lys3614–Asn3643 calmodulin-binding domain with the Cys4114-Asn4142 region of the type 1 ryanodine receptor is involved in the mechanism of Ca2+/agonist-induced channel activation
Biochemical Journal·2008· 23 cited
Identification of Target Domains of the Cardiac Ryanodine Receptor to Correct Channel Disorder in Failing Hearts
Circulation·2008· 80 citedOpen Access
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Frequent Co-authors

Takeshi Yamamoto(12), Shigeki Kobayashi(10), Masafumi Yano(10), Masunori Matsuzaki(10), Hiroki Tateishi(8), Shinichi Okuda(8), Hitoshi Uchinoumi(7), Tetsuro Oda(7), Takeshi Suetomi(6), Xiaojuan Xu(6), Masahiro Doi(6), Yasuhiro Ikeda(6), J. Gergely(6), Bozena Antoniu(6), Makoto Ono(5), Cecilia Hidalgo(4), Mamoru Mochizuki(4), Tomoko Ohkusa(4), Takeshi Yamamoto(4), F. A. Sréter(4)