Hilary Wynne

Freeman Hospital — United Kingdom

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

33h-index4.9kcitations115works0.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(27), Atrial Fibrillation Management and Outcomes(23), Vitamin K Research Studies(16), Blood Pressure and Hypertension Studies(12), Hormonal Regulation and Hypertension(12)

Publications115 total

Assessment of exposure to direct oral anticoagulants in elderly hospitalised patients
British Journal of Haematology·2021· 13 citedOpen Access
Influenza vaccination of at risk adults
2021
Elderly people are inherently sensitive to the pharmacological activity of rivaroxaban: implications for DOAC prescribing
Journal of Thrombosis and Thrombolysis·2020· 12 citedOpen Access
Validation of an algorithm to predict decline in INR following warfarin cessation in patients undergoing invasive procedures
Journal of Thrombosis and Thrombolysis·2019· 3 citedOpen Access
Elderly People are More Sensitive to the Pharmacological Activity of Rivaroxaban: Implications for DOAC Prescribing
SSRN Electronic Journal·2019Open Access
Effect of genetic and patient factors on warfarin pharmacodynamics following warfarin withdrawal: Implications for patients undergoing surgery
Thrombosis Research·2018· 7 cited
Individual and monitoring centre influences upon anticoagulation control of <scp>AF</scp> patients on warfarin: A longitudinal multi‐centre <scp>UK</scp>‐based study
European Journal Of Haematology·2018Open Access
Assessment of the efficacy of a novel tailored vitamin K dosing regimen in lowering the International Normalised Ratio in over‐anticoagulated patients: a randomised clinical trial
British Journal of Haematology·2017· 1 citedOpen Access
Impact of age on long‐term anticoagulation and how gender and monitoring setting affect it: implications for decision making and patient management
British Journal of Clinical Pharmacology·2016· 49 citedOpen Access
VKORC1 (-1639) Polymorphisms do not Affect Long-Term Stability of Anticoagulation with Warfarin
International Journal of Clinical Pharmacology & Toxicology·2015Open Access
Influence of CYP2C9 polymorphism on the fall in International Normalized Ratio in patients interrupting warfarin therapy before elective surgery
Journal of Thrombosis and Haemostasis·2015· 11 cited
The impact of genetics on the management of patients on warfarin awaiting surgery
Age and Ageing·2015· 4 citedOpen Access
Anticoagulation control and cost of monitoring of older patients on chronic warfarin therapy in three settings in North East England
Age and Ageing·2014· 9 citedOpen Access
The Impact Of Dietary Vitamin K On The Pharmacological Activity Of FXa Inhibitor, Rivaroxaban, In Man
Blood·2013
Improving the safety and efficacy of anticoagulation therapy for thromboembolic disease through Vitamin K
2013
Improving the safety and efficacy of anticoagulation therapy
2012
Effect of provision of the NHS NPSA oral anticoagulant therapy patient information pack upon patients’ knowledge and anticoagulant control
Journal of Thrombosis and Haemostasis·2010· 6 cited
Drug treatment in an ageing population: Practical implications
Maturitas·2010· 34 cited
Pharmacogenetics of Warfarin
Annual Review of Medicine·2009· 109 cited
Pharmacogenetics and anticoagulation therapy
2009
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Frequent Co-authors

Farhad Kamali(18), Tayyaba Khan(8), Peter Avery(8), M. D. Rawlins(8), Ken Woodhouse(7), Elizabeth Sconce(6), Peter Wood(6), Patrick Kesteven(6), K.W. Woodhouse(6), D. Nicholas Bateman(5), Ann K. Daly(4), Lance Cope(4), Oliver James(4), B Herd(4), E Mutch(4), O.F.W. James(3), Shl Thomas(3), L. Bevan(3), Sudeepa Bhattacharyya(3), MG Bramble(3)