Douglas B. Young

University of Cape Town — South Africa

Medicine · Health Sciences

59h-index14.5kcitations155works0.02yr avg
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Research Topics

Tuberculosis Research and Epidemiology(108), Mycobacterium research and diagnosis(91), RNA and protein synthesis mechanisms(16), Heat shock proteins research(14), Diagnosis and treatment of tuberculosis(14)

Publications153 total

Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex
Nature Communications·2019· 52 citedOpen Access
Variation in pre-therapy levels of selected Mycobacterium tuberculosis transcripts in sputum and their relationship with 2-month culture conversion
Wellcome Open Research·2019· 3 citedOpen Access
Proteomic and transcriptomic experiments reveal an essential role of RNA degradosome complexes in shaping the transcriptome of Mycobacterium tuberculosis
Nucleic Acids Research·2019· 71 citedOpen Access
Selected Pre-therapy MTB transcripts
Figshare·2019· 1 citedOpen Access
Time course RNA-seq of Mycobacterium tuberculosis exposed to nitric oxide
London School of Hygiene & Tropical Medicine·2017
Structural characterization of CYP144A1 – a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis
Scientific Reports·2016· 10 citedOpen Access
Population Genomics of Mycobacterium tuberculosis in Ethiopia Contradicts the Virgin Soil Hypothesis for Human Tuberculosis in Sub-Saharan Africa
Current Biology·2015· 107 citedOpen Access
Admixture mapping of tuberculosis and pigmentation-related traits in an African–European hybrid cattle population
Frontiers in Genetics·2015· 12 citedOpen Access
Bovine viral diarrhea virus outbreak in a beef cow herd in South Dakota
Journal of the American Veterinary Medical Association·2015· 9 citedOpen Access
Phylogenetic analysis of vitamin B12-related metabolism in Mycobacterium tuberculosis
Frontiers in Molecular Biosciences·2015· 41 citedOpen Access
Lipidomics and genomics of <i>Mycobacterium tuberculosis</i> reveal lineage‐specific trends in mycolic acid biosynthesis
MicrobiologyOpen·2014· 44 citedOpen Access
Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis
Nature·2014· 614 citedOpen Access
Genomic mapping of cAMP receptor protein (CRP<sup>Mt</sup>) in<i>Mycobacterium tuberculosis</i>: relation to transcriptional start sites and the role of CRP<sup>Mt</sup>as a transcription factor
Nucleic Acids Research·2014· 57 citedOpen Access
Immune Intervention in Tuberculosis
ASM Press eBooks·2014· 1 cited
Strategies for New Drug Development
Tuberculosis·2014· 19 cited
Noncoding RNA in Mycobacteria
Microbiology Spectrum·2014· 25 cited
Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis
Cell Reports·2014· 5 citedOpen Access
A Small RNA Encoded in the Rv2660c Locus of Mycobacterium tuberculosis Is Induced during Starvation and Infection
PLoS ONE·2013· 40 citedOpen Access
Defining the Range of Pathogens Susceptible to Ifitm3 Restriction Using a Knockout Mouse Model
PLoS ONE·2013· 91 citedOpen Access
Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis
Cell Reports·2013· 329 citedOpen Access
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Frequent Co-authors

Brian D. Robertson(9), Abraham Aseffa(8), R. Glyn Hewinson(8), Iñaki Comas(7), Graham R. Stewart(7), Stefan Berg(6), Sébastien Gagneux(6), Gobena Ameni(6), Martin Vordermeier(5), Kristine B. Arnvig(4), Stephen V. Gordon(4), Clifton E. Barry(3), Robert J. Wilkinson(3), Julian Parkhill(3), Koen A. L. De Smet(3), I.N. Brown(3), Gordon Dougan(3), Rebuma Firdessa(3), Elena Hailu(3), Teklu Kiros(3)