Bernat Vidal

Almirall (Spain) — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index912citations54works0.02yr avg
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Research Topics

Adenosine and Purinergic Signaling(13), Asymmetric Synthesis and Catalysis(11), Alkaloids: synthesis and pharmacology(11), Synthesis and Biological Evaluation(10), Chemical synthesis and alkaloids(9)

Publications54 total

Prediction of the skin permeability of topical drugs using in silico and in vitro models
European Journal of Pharmaceutical Sciences·2019· 32 cited
Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists
European Journal of Medicinal Chemistry·2016· 18 citedOpen Access
A novel inhaled Syk inhibitor blocks mast cell degranulation and early asthmatic response
Pharmacological Research·2015· 25 cited
Discovery of 7-azaindole derivatives as potent Orai inhibitors showing efficacy in a preclinical model of asthma
Bioorganic & Medicinal Chemistry Letters·2015· 21 citedOpen Access
Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists I
Bioorganic & Medicinal Chemistry Letters·2014· 8 citedOpen Access
Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists II: Lead optimization
Bioorganic & Medicinal Chemistry Letters·2014· 5 citedOpen Access
Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists III: The role of a hydrogen-bond acceptor in long receptor residence times
Bioorganic & Medicinal Chemistry Letters·2014· 10 citedOpen Access
Study of the aggregation process of the amyloid beta-protein associated to Alzheimer's disease. Examination of pharmaceutically important small molecules.
TDX (Tesis Doctorals en Xarxa)·2014
Highly potent aminopyridines as Syk kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2012· 20 citedOpen Access
SYK in COMPLEX WITH LIGAND LASW836
2012
Novel triazolopyridylbenzamides as potent and selective p38α inhibitors
Bioorganic & Medicinal Chemistry Letters·2012· 33 citedOpen Access
Pyrazine-based Syk kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2012· 17 citedOpen Access
1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase
Journal of Medicinal Chemistry·2011· 31 citedOpen Access
Indolin-2-one p38α inhibitors I: Design, profiling and crystallographic binding mode
Bioorganic & Medicinal Chemistry Letters·2011· 28 citedOpen Access
Discovery of LAS101057: A Potent, Selective, and Orally Efficacious A<sub>2B</sub> Adenosine Receptor Antagonist
ACS Medicinal Chemistry Letters·2010· 18 citedOpen Access
ChemInform Abstract: Synthesis and Pharmacological Evaluation of Novel Substituted 9‐Deazaxanthines as A<sub>2B</sub> Receptor Antagonists.
ChemInform·2010
Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists
European Journal of Medicinal Chemistry·2010· 10 citedOpen Access
Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A2B adenosine receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2010· 19 citedOpen Access
Discovery of potent and selective bicyclic A2B adenosine receptor antagonists via bioisosteric amide replacement
Bioorganic & Medicinal Chemistry Letters·2010· 21 citedOpen Access
Design, Synthesis, and Structure−Activity Relationships of Aminopyridine<i>N</i>-Oxides, a Novel Scaffold for the Potent and Selective Inhibition of p38 Mitogen Activated Protein Kinase
Journal of Medicinal Chemistry·2009· 33 citedOpen Access
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Frequent Co-authors

Cristina Esteve(18), Joan Bosch(17), M.-Lluı̈sa Bennasar(16), Marı́a Isabel Loza(11), Jacob González(10), Marı́a Isabel Cadavid(8), Paul Eastwood(8), Laura Vidal(8), Adelina Orellana(7), Vı́ctor Segarra(6), Arsenio Nueda(6), José Brea(6), María Domínguez(5), Marta Calbet(5), Montserrat Miralpeix(5), Juan Antonio Alonso(5), Cristina Balagué(4), Francisco Caturla(4), Núria Godessart(4), Teresa Domènech(4)