Da-Cheng Zhou

Montefiore Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index452citations20works0.02yr avg
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Research Topics

Retinoids in leukemia and cellular processes(12), Acute Myeloid Leukemia Research(9), Drug Transport and Resistance Mechanisms(6), Advanced biosensing and bioanalysis techniques(3), Cancer therapeutics and mechanisms(3)

Publications20 total

Treatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia
Blood·2012· 54 citedOpen Access
Clonal Markers In Relapsed Acute Promyelocytic Leukemia (APL): Clinicopathological Associations and Relation to All-Trans Retinoic Acid (ATRA) Treatment on Intergroup Phase III Trial C9710.
Blood·2010
Increased Global Gene Promoter Methylation after Relapse (Rel) of Acute Promyelocytic Leukemia (APL) from All-trans Retinoic Acid (ATRA)-Containing Treatment Is Dissociated from Concurrent Gene Expression Changes.
Blood·2007· 7 cited
Treatment Type Determines Gene Expression Changes from Pretreatment (PTx) to Relapse (Rel) in Acute Promyelocytic Leukemia (APL).
Blood·2007
Lack of Increased Gene Promoter Methylation at Relapse in Acute Promyelocytic Leukemia (APL).
Blood·2006
DNA Methylation Independent Silencing of the RARα Gene Expression in Acute Myeloid Leukemia.
Blood·2006
Mutation of Cellular Retinoic Acid-Binding Protein-II (Crabp-II) Does Not Account for Resistance to All-Trans Retinoic Acid (ATRA) in Relapse Acute Promyelocytic Leukemia (APL).
Blood·2004
Pyrosequencing Analysis of the Methylation Status of the CpG Island in the Retinoic Acid Receptor-β2 (RAR-β2) Gene Promoter.
Blood·2004
Relapse of Acute Promyelocytic Leukemia (APL) Is Associated with Increased Methylation of the Retinoic Acid Receptor-Beta2 (RARβ2) Gene Promoter.
Blood·2004
Frequent mutations in the ligand-binding domain of PML-RARα after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-transretinoic acid and histone deacetylase inhibitors in vitro and in vivo
Blood·2002· 118 cited
Altered ligand binding and transcriptional regulation by mutations in the PML/RARα ligand-binding domain arising in retinoic acid–resistant patients with acute promyelocytic leukemia
Blood·2000· 3 cited
Altered ligand binding and transcriptional regulation by mutations in the PML/RARα ligand-binding domain arising in retinoic acid–resistant patients with acute promyelocytic leukemia
Blood·2000· 65 cited
Sequential emergence ofMRP- andMDR1-gene over-expression as well asMDR1-gene translocation in homoharringtonine-selected K562 human leukemia cell lines
International Journal of Cancer·1996· 58 citedOpen Access
Expression of multidrug resistance-associated protein (MRP) gene in acute myeloid leukemia and correlation with expression of multidrug resistance (MDR1)gene
Anti-Cancer Drugs·1994· 1 cited
In vitro reversal of multidrug resistance (MDR1) in hematopoietic cell lines by GF120918, a new modifying agent of P-glycoprotein
Anti-Cancer Drugs·1994
DNA-topoisomerase I and II: biologic features and their role in drug resistance.
PubMed·1994· 4 cited
Expression of Resistance Genes in Acute Leukemia
Leukemia & lymphoma/Leukemia and lymphoma·1994· 12 cited
Effect of differentiating agents on modulation of MDR1 gene expression in multidrug-resistant hematopoietic HL60/DNR cell line.
PubMed·1993· 15 cited
Relevance of mdr1 gene expression in acute myeloid leukemia and comparison of different diagnostic methods.
PubMed·1992· 100 cited
Multidrug Resistance (MDR) Gene Expression in Acute Non Lymphoblastic Leukemia: Sequential Analysis
Leukemia & lymphoma/Leukemia and lymphoma·1992· 15 cited

Frequent Co-authors

Robert E. Gallagher(12), R Zittoun(6), Martin S. Tallman(4), Jean‐Pierre Marie(4), Haesook Kim(4), J. P. Marie(3), Anne‐Marie Suberville(3), Sylvie Côté(2), Andrea Bianchini(2), Clara Nervi(2), Wilson H. Miller(2), Anne‐Marie Faussat(2), Barry Kurt Moser(2), Janis Racevskis(2), Xavier Poiré(2), Clara D. Bloomfield(2), Andrew J. Carroll(2), Esther Schachter-Tokarz(2), I-Ming L. Chen(2), Richard C. Harvey(2)