Friedrich E. Kruse

Friedrich-Alexander-Universität Erlangen-Nürnberg — Germany

Medicine · Health Sciences

75h-index19.1kcitations626works2.22yr avg
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Research Topics

Corneal surgery and disorders(247), Corneal Surgery and Treatments(245), Glaucoma and retinal disorders(203), Ocular Surface and Contact Lens(118), Retinal Diseases and Treatments(51)

Publications624 total

Secondary Graft Failure After Descemet Membrane Endothelial Keratoplasty: Clinical Characteristics and Ultrastructural Findings of Failed Grafts
Cornea·2025
Enhanced mitochondria-associated membrane formation in Fuchs endothelial corneal dystrophy: a novel link between endoplasmic reticulum stress and mitochondrial dysfunction
Japanese Journal of Ophthalmology·2025· 1 cited
Establishment of an Advanced In Vitro Model for Pseudoexfoliation Syndrome and Glaucoma
Investigative Ophthalmology & Visual Science·2025Open Access
Amnion-ummantelte Bio-Inlays zur Behandlung einer schweren pseudomembranösen Keratokonjunktivitis bei 2 Patienten mit Erythema exsudativum multiforme nach einer Mycoplasma-pneumoniae-induzierten Pneumonie
Die Ophthalmologie·2025Open Access
The PERK–p38 MAPK Axis Drives Endoplasmic Reticulum Stress-Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy
Investigative Ophthalmology & Visual Science·2025· 1 citedOpen Access
Safety, tolerability and clinical effects of rovunaptabin, also known as BC007 on fatigue and quality of life in patients with Post-COVID syndrome (reCOVer): a prospective, exploratory, placebo-controlled, double-blind, randomised phase IIa clinical trial (RCT)
EClinicalMedicine·2025· 4 citedOpen Access
Comprehensive analysis of splicing variants in corneal endothelial cells of patients with Fuchs endothelial corneal dystrophy
Scientific Reports·2025· 2 citedOpen Access
A feasibility of computational drug screening for Fuchs endothelial corneal dystrophy
Scientific Reports·2025Open Access
Comprehensive identification of dysregulated extracellular matrix molecules in the corneal endothelium of patients with Fuchs endothelial corneal dystrophy
Scientific Reports·2025· 3 citedOpen Access
TCF4 expansion–associated loss of FN1 intron retention drives extracellular matrix accumulation in Fuchs endothelial corneal dystrophy
Experimental Eye Research·2025
Therapeutic Potential of Emricasan, a Pan-Caspase Inhibitor, in Reducing Cell Death and Extracellular Matrix Accumulation in Fuchs Endothelial Corneal Dystrophy
Cells·2025· 3 citedOpen Access
Involvement of TGF-β signaling pathway-associated genes in the corneal endothelium of patients with Fuchs endothelial corneal dystrophy
Experimental Eye Research·2025· 2 cited
The <i>TCF4</i> Gene Regulates Apoptosis of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy
Investigative Ophthalmology & Visual Science·2025· 4 citedOpen Access
Transcriptional Profiling of Patients With Fuchs Endothelial Corneal Dystrophy With and Without Trinucleotide Repeat Expansion in TCF4
Cornea·2025· 2 cited
Drug- and Cell-Type-Specific Effects of ROCK Inhibitors as a Potential Cause of Reticular Corneal Epithelial Edema
Cells·2025· 7 citedOpen Access
Sex-Dependent Variations in Gene Expression in Corneal Endothelial Cells Among Healthy Individuals and Patients With Fuchs Endothelial Corneal Dystrophy
Cornea·2025· 1 cited
Limbal Stem Cell Deficiency
2025
Safety, tolerability and clinical effects of BC007 (Rovunaptabin) on fatigue and quality of life in patients with post-COVID syndrome (reCOVer): a prospective, exploratory, randomised, placebo-controlled, double-blind, crossover phase IIa clinical trial
2024· 1 citedOpen Access
Keratomalacia and corneal perforation in vitamin A deficiency: Anterior-segment optical-coherence-tomography and histological findings
American Journal of Ophthalmology Case Reports·2024· 2 citedOpen Access
Descemet Membrane Endothelial Keratoplasty for Endothelial Failure in Primary Angle Closure Suspects
Cornea·2024· 1 cited
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Frequent Co-authors

Claus Cursiefen(17), Ursula Schlötzer‐Schrehardt(12), Björn Bachmann(10), Kathrin Laaser(6), Felix Bock(5), Matthias Zenkel(5), Gottfried O.H. Naumann(5), Theofilos Tourtas(4), Klaus Rohrschneider(4), Paolo Rama(4), Folkert K. Horn(4), Reza Dana(3), Francisco C. Figueiredo(3), Tina Dietrich-Ntoukas(3), Ludwig M. Heindl(3), Carmen Hofmann-Rummelt(3), Francesca Pasutto(3), André Reis(3), Ursula Schlo ̈tzer-Schrehardt(3), Sophie X. Deng(2)