Dorothy J. Donnelly

Trinity College Dublin — Ireland

Medicine · Health Sciences

9h-index471citations17works0.02yr avg
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Research Topics

Synthesis of Organic Compounds(8), Synthesis and biological activity(5), Oxidative Organic Chemistry Reactions(4), DNA Repair Mechanisms(3), Glioma Diagnosis and Treatment(3)

Publications17 total

QSAR and Chemical Read-Across Analysis of 370 Potential MGMT Inactivators to Identify the Structural Features Influencing Inactivation Potency
Pharmaceutics·2023· 26 citedOpen Access
Comparison of the occurrence of rot in sawlogs from regrowth and mature stands of <i>Eucalyptus diversicolor</i> (karri)
Australian Forestry·2008· 5 cited
Lomeguatrib, a Potent Inhibitor of <i>O</i>6-Alkylguanine-DNA-Alkyltransferase: Phase I Safety, Pharmacodynamic, and Pharmacokinetic Trial and Evaluation in Combination with Temozolomide in Patients with Advanced Solid Tumors
Clinical Cancer Research·2006· 142 citedOpen Access
Effect of <i>O</i><sup>6</sup>‐(4‐bromothenyl)guanine on different temozolomide schedules in a human melanoma xenograft model
International Journal of Cancer·2002· 42 cited
O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts
International Journal of Cancer·2000· 77 cited
O6-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts
International Journal of Cancer·2000· 53 citedOpen Access
Inactivation of <i>O</i><sup>6</sup>-Alkylguanine-DNA Alkyltransferase. 1. Novel <i>O</i><sup>6</sup>-(Hetarylmethyl)guanines Having Basic Rings in the Side Chain
Journal of Medicinal Chemistry·1998· 68 citedOpen Access
ChemInform Abstract: NITRATION, AMINATION, AND HALOGENATION OF DI‐O‐METHYLPHLORACETOPHENONE
Chemischer Informationsdienst·1982
Nitration, amination, and halogenation of Di-O-methylphloracetophenone
Monatshefte für Chemie - Chemical Monthly·1982· 4 cited
ChemInform Abstract: CHALCONE DIHALIDES. IX. THE MODES OF CYCLIZATION OF 4‐NITROCHALCONE DIBROMIDES AND α‐BROMO‐4‐NITROCHALCONES
Chemischer Informationsdienst·1978
Chalcone dihalides—IX
Tetrahedron·1977· 9 cited
ChemInform Abstract: DIHALOGENCHALKONE 3. MITT. CYCLISIERUNG VON NITROCHALKONDIBROMIDEN
Chemischer Informationsdienst·1972
ChemInform Abstract: CHALKONDIHALOGENIDE 2. MITT. AEHNLICHKEIT DES EINFLUSSES DER 2‐THIENYL‐ UND 4‐METHOXY‐PHENYL‐GRUPPE IN DER SEITENKETTE
Chemischer Informationsdienst·1972
Chalcone dihalides—II
Tetrahedron·1972· 12 cited
Chalcone dihalides—III
Tetrahedron·1972· 8 cited
Steric effects on the cyclisation of chalcone dibromides
Chemical Communications (London)·1966· 4 cited
Synthesis of Heterocyclic-Substituted Chromones and Related Compounds as Potential Anticancer Agents<sup>1</sup>
Journal of Medicinal Chemistry·1965· 21 cited

Frequent Co-authors

J. A. DONNELLY(9), R. Stanley McElhinney(6), Geoffrey P. Margison(6), E.M. Philbin(6), Mark R. Middleton(5), T. Brian H. McMurry(5), Jane Kelly(4), Joan E. McCormick(4), Nicholas Thatcher(3), T. S. Wheeler(2), J. R. KEEGAN(2), John P. Acton(2), Malcolm Ranson(1), John Bridgewater(1), Siow Ming Lee(1), Martin D. Dawson(1), Debra Jowle(1), Gavin Halbert(1), S. Waller(1), Helen E. McGrath(1)