Esther Vock

Boehringer Ingelheim (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index646citations21works19.02yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(12), Computational Drug Discovery Methods(6), Metabolomics and Mass Spectrometry Studies(4), Indoor Air Quality and Microbial Exposure(3), Synthesis and Biological Evaluation(3)

Publications21 total

Quantum Chemical Evaluation and QSAR Modeling of <i>N</i>-Nitrosamine Carcinogenicity
Chemical Research in Toxicology·2025· 7 cited
In Silico Prediction of Oral Acute Rodent Toxicity Using Consensus Machine Learning
Journal of Chemical Information and Modeling·2024· 7 cited
Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic Potency
Chemical Research in Toxicology·2024· 43 cited
eTRANSAFE: data science to empower translational safety assessment
Nature Reviews Drug Discovery·2023· 19 citedOpen Access
Acceptable intakes (AIs) for 11 small molecule N-nitrosamines (NAs)
Regulatory Toxicology and Pharmacology·2023· 29 citedOpen Access
Development of Pharmacophore Models for the Important Off-Target 5-HT<sub>2B</sub> Receptor
Journal of Medicinal Chemistry·2023· 7 cited
Evaluation of Pharmaceuticals for DNA Damage in the Chicken Egg Genotoxicity Assay (CEGA)
International Journal of Toxicology·2022· 4 cited
Development of an in silico consensus model for the prediction of the phospholipigenic potential of small molecules
Computational Toxicology·2022· 7 cited
Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond
Chemical Research in Toxicology·2019· 11 cited
DNA-damaging activities of twenty-four structurally diverse unsubstituted and substituted cyclic compounds in embryo-fetal chicken livers
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2019· 12 cited
Expression of Genes Encoding for Xenobiotic Metabolism After Exposure to Dialkylnitrosamines in the Chicken Egg Genotoxicity Alternative Model
Toxicological Sciences·2018· 13 citedOpen Access
Legacy data sharing to improve drug safety assessment: the eTOX project
Nature Reviews Drug Discovery·2017· 70 citedOpen Access
Chicken Fetal Liver DNA Damage and Adduct Formation by Activation-Dependent DNA-Reactive Carcinogens and Related Compounds of Several Structural Classes
Toxicological Sciences·2014· 26 citedOpen Access
Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities
Regulatory Toxicology and Pharmacology·2013· 123 cited
Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2010· 109 cited
Immortalization Strategies for Epithelial Cells in Primary Culture
2007· 3 cited
Trans- and cis-DNA adduct concentration in epidermis from mouse and rat skin treated ex vivo with benzo[a]pyrene diol epoxide and its corresponding chlorohydrin
Mutation research. Fundamental and molecular mechanisms of mutagenesis·2001· 8 cited
Distribution and DNA adduct formation of radiolabeled methylenediphenyl-4,4′-diisocyanate (MDI) in the rat after topical treatment
Toxicology Letters·1997· 22 cited
On the Role of DNA Double-Strand Breaks in Toxicity and Carcinogenesis
Critical Reviews in Toxicology·1997· 113 cited
32P-postlabeling analysis of DNA adducts formed in vitro and in rat skin by methylenediphenyl-4,4'-diisocyanate (MDI)
Toxicology Letters·1995· 13 cited
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Frequent Co-authors

Sebastian Schieferdecker(5), Wolfgang Muster(4), Gary M. Williams(4), Jian‐Dong Duan(4), Ulrich Deschl(4), Alexander Amberg(3), Laura Custer(3), Nigel Greene(3), Werner K. Lutz(3), Andreas Czich(3), Klaus D. Brunnemann(3), Tetyana Kobets(3), Andreas Sutter(2), Alessandro Brigo(2), Krista L. Dobo(2), Susanne Glowienke(2), M. Vijayaraj Reddy(2), Véronique Thybaud(2), Ferrán Sanz(2), François Pognan(2)