Edwin R. Speck

SUNY Upstate Medical University — United States

Medicine · Health Sciences

19h-index2.0kcitations50works0.02yr avg
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Research Topics

Platelet Disorders and Treatments(26), Blood groups and transfusion(16), Blood transfusion and management(12), Blood disorders and treatments(8), Immune Response and Inflammation(7)

Publications49 total

99EMF A Retrospective Study of a Novel Prediction Tool for Assessing Those at Risk for Firearm Violence
Annals of Emergency Medicine·2023Open Access
Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP)
Platelets·2019· 52 citedOpen Access
Persistence of de novo DSA is associated with chronic lung allograft dysfunction and reduced survival after lung transplantation
Pneumologie·2019
Gastrointestinal microbiota contributes to the development of murine transfusion-related acute lung injury
Blood Advances·2018· 60 citedOpen Access
Gastrointestinal Flora Dictates the Biological Response in Murine Transfusion Related Acute Lung Injury (TRALI)
Blood·2017· 3 cited
A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (<scp>ITP</scp>)
British Journal of Haematology·2017· 12 citedOpen Access
Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets
Blood Advances·2017· 127 citedOpen Access
T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10
Blood·2017· 116 citedOpen Access
Interleukin (IL)-10 Is an Effective Therapeutic for Murine Transfusion Related Acute Lung Injury (TRALI)
Blood·2016· 1 cited
DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis
American Journal of Respiratory and Critical Care Medicine·2016· 109 citedOpen Access
Naturally processed heterodimeric disulfide-linked insulin peptides bind to major histocompatibility class II molecules on thymic
2016
Murine Bone Marrow-Derived Megakaryocytes Are Capable of Antigen Cross-Presentation on Major Histocompatibility Class (MHC) I Molecules
Blood·2015· 3 cited
C-Reactive Protein (CRP) Enhances Murine Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)
Blood·2015· 1 cited
CD4+CD25+Foxp3+ T Regulatory Cells Protect Against Murine Antibody-Mediated Transfusion-Related Acute Lung Injury (TRALI)
Blood·2015
Successful Treatment of Thrombocytopenia with Staphylococcal Protein A (PRTX-100) in a Murine Model of Immune Thrombocytopenia (ITP)
Blood·2015
Thymic-Derived Tolerizing Dendritic Cells Are up-Regulated upon Treatment with Intravenous Immunoglobulin or Splenectomy in a Murine Model of Immune Thrombocytopenia
Blood·2015· 1 cited
CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell–mediated immune thrombocytopenia
Blood·2015· 57 citedOpen Access
CD20 B Cell Depleting Therapy Is Associated with up-Regulation of CD8+CD25highFoxp3+ T Regulatory Cells in a Murine Model of Immune Thrombocytopenia (ITP)
Blood·2014
Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia
Blood·2013· 31 cited
Megakaryocyte Abnormalities Occur In The Absence Of Cell-Mediated Immunity In a Murine Model Of Passive Immune Thrombocytopenia (ITP)
Blood·2013
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Frequent Co-authors

John W. Semple(43), Rukhsana Aslam(27), Michael Kim(20), John Freedman(18), Heyu Ni(13), Rick Kapur(12), Li Guo(11), Alan H. Lazarus(9), Anne Zufferey(8), Leola Chow(4), John Freedman(4), Pingguo Chen(3), Mark J. McVey(3), Jonathan Liu(3), Shanjeevan Shanmugabhavananthan(3), Johan Rebetz(3), Noel N. Kim(3), Victor S. Blanchette(3), Terry L. Delovitch(3), Frédérique Forquet(3)