Luba Roncari

Mount Sinai Hospital — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index3.2kcitations18works0.02yr avg
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Research Topics

Angiogenesis and VEGF in Cancer(6), Glioma Diagnosis and Treatment(5), Cancer, Hypoxia, and Metabolism(4), Ubiquitin and proteasome pathways(3), Neurofibromatosis and Schwannoma Cases(3)

Publications18 total

A role for the TGFβ-Par6 polarity pathway in breast cancer progression
Proceedings of the National Academy of Sciences·2009· 122 citedOpen Access
Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases
Cell·2009· 329 citedOpen Access
An experimentally derived confidence score for binary protein-protein interactions
Nature Methods·2008· 442 citedOpen Access
Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.
PubMed·2003· 137 cited
762 Overexpression of EGFRvIII Potentiates the Development and Aggressiveness of Astrocytomas in an Activated Ras Transgenic Mouse Astrocytoma Model
Neurosurgery·2001
762 Overexpression of EGFRvIII Potentiates the Development and Aggressiveness of Astrocytomas in an Activated Ras Transgenic Mouse Astrocytoma Model
Neurosurgery·2001
Isotype-specific Ras.GTP-levels predict the efficacy of farnesyl transferase inhibitors against human astrocytomas regardless of Ras mutational status.
PubMed·2001· 91 cited
Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.
PubMed·2001· 275 cited
Expression and hypoxic regulation of angiopoietins in humanastrocytomas
Neuro-Oncology·2001· 65 citedOpen Access
Expression and hypoxic regulation of angiopoietins in human astrocytomas
Neuro-Oncology·2001· 6 cited
Expression of vascular endothelial growth factor by reactive astrocytes and associated neoangiogenesis
Brain Research·2000· 66 cited
Loss of Neurofibromin Is Associated with Activation of RAS/MAPK and PI3-K/AKT Signaling in a Neurofibromatosis 1 Astrocytoma
Journal of Neuropathology & Experimental Neurology·2000· 158 cited
764 Transgenic Mouse Model of Malignant Astrocytoma: Specific Astrocyte Specific Expression of Activated RAS
Neurosurgery·2000· 2 cited
Expression and regulation of neuropilin-1 in human astrocytomas
International Journal of Cancer·2000· 72 citedOpen Access
Expression of Activated Epidermal Growth Factor Receptors, Ras-Guanosine Triphosphate, and Mitogen-activated Protein Kinase in Human Glioblastoma Multiforme Specimens
Neurosurgery·1999· 224 cited
Inhibition of angiogenesis by blocking activation of the vascular endothelial growth factor receptor 2 leads to decreased growth of neurogenic sarcomas.
PubMed·1999· 106 cited
Impact of oncogenes in tumor angiogenesis: Mutant K- <i>ras</i> up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells
Proceedings of the National Academy of Sciences·1998· 264 cited
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer
Nature Medicine·1997· 843 cited

Frequent Co-authors

Abhijit Guha(10), Nelson C. Lau(9), Patrick Shannon(7), András Nagy(7), David H. Gutmann(6), Hao Ding(5), Xiaoli Wu(5), Xiaoli Wu(4), Jeffrey L. Wrana(3), Abhijit Guha(3), P. V. R. SHANNON(3), Masahiro Narimatsu(2), Rohit Bose(2), A. Guha(2), Robert S. Kerbel(2), Matthias M. Feldkamp(2), Nelson Lau(2), Matthias M. Feldkamp(2), Hao Ding(2), Lilyana Angelov(2)