R. Dotson

Novartis (Switzerland) — Switzerland

Medicine · Health Sciences

4h-index101citations12works0.02yr avg
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Research Topics

Inflammatory mediators and NSAID effects(4), Synthesis and Reactivity of Sulfur-Containing Compounds(3), Chemical Synthesis and Analysis(2), Synthesis of Organic Compounds(2), Synthesis and Biological Evaluation(2)

Publications12 total

ChemInform Abstract: Thia‐Prostanoid Analogues with Combined Thromboxane Receptor Antagonist/Thromboxane Synthase Inhibitor Activities. Synthesis and Pharmacological Evaluation.
ChemInform·1995
ChemInform Abstract: Oxa‐Prostanoid Analogues. Identification of an Orally Effective, Dual Thromboxane Receptor Antagonist (TxRA)/Thromboxane Synthase Inhibitor.
ChemInform·1995
Thia-prostanoid analogs with combined thromboxane receptor antagonist/thromboxane synthase inhibitor activities. Synthesis and pharmacological evaluation
Bioorganic & Medicinal Chemistry Letters·1994· 3 cited
Marked reduction of LDL and Lp(a) by CGS 26214, a selective cardiac-sparing thyromimetic in cynomolgus monkeys
Atherosclerosis·1994· 1 cited
Oxa-prostanoid analogs. Identification of an orally effective, dual thromboxane receptor antagonist /thromboxane synthase inhibitor
Bioorganic & Medicinal Chemistry Letters·1994· 4 cited
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 5. Synthesis and evaluation of enantiomers of 8-[[(4-chlorophenyl)sulfonyl]amino]-4-(3-pyridinylalkyl)octanoic acid
Journal of Medicinal Chemistry·1993· 17 citedOpen Access
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 7. pyridinylalkyl-substituted arylsulfonylamino arylalkanoic acids.
Bioorganic & Medicinal Chemistry Letters·1992· 7 cited
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 6. 4-substituted 3-pyridinylalkanoic acids.
Bioorganic & Medicinal Chemistry Letters·1992· 2 cited
Characterization of CGS 8515 as a selective 5-lipoxygenase (5-LO) inhibitor.
PubMed·1989· 3 cited
Pharmacological characterization of CGS 15943A: a novel nonxanthine adenosine antagonist.
Journal of Pharmacology and Experimental Therapeutics·1987· 59 cited
Effect of simultaneously ingested milk on phenytoin bioavailability
Neurology·1985· 5 cited
ChemInform Abstract: SYNTHESIS AND DIURETIC PROFILE OF 3‐(3‐AMINO‐1,2,4‐OXADIAZOL‐5‐YL)‐5‐CHLORO‐2,6‐PYRAZINEDIAMINE, AN AMILORIDE‐TYPE DIURETIC
Chemischer Informationsdienst·1980

Frequent Co-authors

Janice Mathis(7), David S. Cohen(6), Isidoros Vlattas(4), James Dellureficio(4), Francis Clarke(4), H. Zoganas(4), Shripad S. Bhagwat(3), Candido Gude(3), W. Lee(3), Geetha Ghai(2), W. LEE(2), J. E. Francis(1), Michael Williams(1), Marlene F. Hopkins(1), Donald Coté(1), Frank R. Goodman(1), M. Bridget Zimmerman(1), David Steven Cohen(1), Warren Lee(1), Patricia Furness(1)