James G. Hecker

University of Washington — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index904citations39works0.02yr avg
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Research Topics

Virus-based gene therapy research(12), RNA Interference and Gene Delivery(12), Heat shock proteins research(5), Cardiac, Anesthesia and Surgical Outcomes(4), Advanced biosensing and bioanalysis techniques(3)

Publications38 total

Assessment of aerosol persistence in ICUs via low-cost sensor network and zonal models
Scientific Reports·2023· 7 citedOpen Access
Measuring aerosols in the operating theatre and beyond using a real‐time sensor network
Anaesthesia·2022· 8 cited
Non-Viral Delivery of RNA Gene Therapy to the Central Nervous System
Pharmaceutics·2022· 17 citedOpen Access
Inadvertent Burst Suppression During Total Intravenous Anesthesia in 112 Consecutive Patients Undergoing Spinal Instrumentation Surgery: A Retrospective Observational Quality Improvement Project
Journal of Neurosurgical Anesthesiology·2021· 13 cited
Gene Therapy for Neuroanesthesia
2019
Incidence and Risk Factors for Intraoperative Seizures During Elective Craniotomy
Journal of Neurosurgical Anesthesiology·2018· 17 cited
Guideline Adherence and Outcomes in Severe Adult Traumatic Brain Injury for the CHIRAG (Collaborative Head Injury and Guidelines) Study
World Neurosurgery·2016· 64 citedOpen Access
Non-Viral, Lipid-Mediated DNA and mRNA Gene Therapy of the Central Nervous System (CNS): Chemical-Based Transfection
Methods in molecular biology·2015· 29 cited
Educational Resources in Neuroanesthesiology
ASA Monitor·2015
. Cerebral Ischemia and Neuroprotection
Oxford University Press eBooks·2013· 3 cited
Nonviral, Cationic Lipid-Mediated Delivery of mRNA
Methods in molecular biology·2012· 5 cited
Clinical experience with intraoperative jugular venous oximetry during pediatric intracranial neurosurgery
Pediatric Anesthesia·2012· 20 cited
A Single Intrathecal Injection of DNA and an Asymmetric Cationic Lipid as Lipoplexes Ameliorates Experimental Autoimmune Encephalomyelitis
Molecular Pharmaceutics·2011· 8 cited
Neuroprotection
Elsevier eBooks·2011
Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: a review and comparison to other methods of detection in thoracic aneurysm repair
Cell Stress and Chaperones·2010· 72 citedOpen Access
The Benefit of Hydrophobic Domain Asymmetry on the Efficacy of Transfection as Measured by <i>in Vivo</i> Imaging
Molecular Pharmaceutics·2010· 34 cited
Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells
International Journal of Pharmaceutics·2010· 159 cited
Antioxidant enzyme gene transfer for ischemic diseases
Advanced Drug Delivery Reviews·2009· 80 citedOpen Access
Whole Animal In Vivo Imaging After Transient, Nonviral Gene delivery to the Rat Central Nervous System
Molecular Therapy·2008· 23 citedOpen Access
A Flexible Method for the Conjugation of Aminooxy Ligands to Preformed Complexes of Nucleic Acids and Lipids
ChemMedChem·2008· 9 cited
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Frequent Co-authors

Michael H. Nantz(7), Shaomin Zou(5), Keith Scarfo(5), Van R. Irion(4), Deepak Sharma(3), Ellen Hauck(3), Michael L. McGarvey(2), Leon L. Hall(2), Monica S. Vavilala(2), Brendan Hilliard(2), Joseph E. Bavaria(2), Michele Furman(2), Jiayang He(2), R. Rochlin(2), Selina Teng(2), K. Glenn(2), Igor Novosselov(2), Tom Kelton(2), Heather McClung(2), W. Andrew Kofke(2)