H. Hank Simms

Royal Stoke University Hospital — United Kingdom

Immunology and Microbiology · Life Sciences

36h-index4.1kcitations138works0.02yr avg
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Research Topics

Immune Response and Inflammation(40), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(23), Cell Adhesion Molecules Research(19), Sepsis Diagnosis and Treatment(14), Neuropeptides and Animal Physiology(14)

Publications138 total

P88 Is Hydrogen Cyanide a Marker of Burkholderia Cepacia Complex Infection?
Thorax·2012· 1 citedOpen Access
Preoperative staging of suspicious pulmonary nodules with combined PET-CT: Concordance of clinical and pathological staging
Journal of the American College of Surgeons·2011
Sexual behaviour, condom use and rates of sexually transmitted infections in HIV clinic attendees in South East London
International Journal of STD & AIDS·2009· 17 cited
Vasoactive Hormone Adrenomedullin and Its Binding Protein: Anti-Inflammatory Effects by Up-Regulating Peroxisome Proliferator-Activated Receptor-γ
The Journal of Immunology·2007· 50 citedOpen Access
Ghrelin Down-regulates Proinflammatory Cytokines in Sepsis Through Activation of the Vagus Nerve
Annals of Surgery·2007· 192 citedOpen Access
Adrenomedullin and adrenomedullin binding protein-1 prevent metabolic acidosis after uncontrolled hemorrhage in rats
Critical Care Medicine·2007· 12 cited
Adrenomedullin and adrenomedullin-binding protein-1 downregulate inflammatory cytokines and attenuate tissue injury after gut ischemia-reperfusion
Surgery·2006· 48 cited
Suppression of hepatocyte CYP1A2 expression by Kupffer cells via AhR pathway: The central role of proinflammatory cytokines
International Journal of Molecular Medicine·2006· 35 citedOpen Access
The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-γ*
Critical Care Medicine·2006· 174 cited
Proapoptotic effect of curcumin on human neutrophils: Activation of the p38 mitogen-activated protein kinase pathway*
Critical Care Medicine·2005· 57 cited
Mechanisms Responsible for Vascular Hyporesponsiveness to Adrenomedullin after Hemorrhage
Annals of Surgery·2005· 19 citedOpen Access
Divergent roles of murine neutrophil chemokines in hemorrhage induced priming for acute lung injury
Cytokine·2005· 19 cited
Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage
Critical Care Medicine·2005· 37 cited
A novel approach to maintaining cardiovascular stability after hemorrhagic shock: Beneficial effects of adrenomedullin and its binding protein
Surgery·2005· 19 cited
Gut-derived norepinephrine plays an important role in up-regulating IL-1β and IL-10
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2004· 32 cited
MECHANISM OF THE IMPROVEMENT OF ORGAN PERFUSION BY GHRELIN IN SEVERE SEPSIS: DOWNREGULATION OF ENDOTHELIN-1
Critical Care Medicine·2004
Regulation of polymorphonuclear leukocyte apoptosis: role of lung endothelium-epithelium bilayer transmigration
American Journal of Physiology-Lung Cellular and Molecular Physiology·2004· 27 cited
Pro-apoptotic effect of curcumin on human polymorphonuclear leukocytes (PMNS): Decreased nuclear NF-KB activity
Journal of Surgical Research·2004
NF-κB protects lung epithelium against hyperoxia-induced nonapoptotic cell death–oncosis
Free Radical Biology and Medicine·2004· 51 cited
Delayed administration of human inter-α inhibitor proteins reduces mortality in sepsis
Critical Care Medicine·2004· 43 cited
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Frequent Co-authors

Ping Wang(17), Mian Zhou(12), Rongqian Wu(9), Xiaoxuan Cui(9), Alfred Ayala(9), Stephanie J. Leuenroth(7), Patricia S. Grutkoski(6), Corrado P. Marini(5), Weifeng Dong(5), Maowen Hu(4), John McNelis(3), William G. Cioffi(3), Chun‐Shiang Chung(3), Joanne L. Lomas(3), Grace Y. Song(3), Annmarie L. Dunican(3), Hugh S. Keeping(3), Shaolong Yang(3), Edmund J. Miller(3), Ronald D’Amico(3)