Steven M. Pitzenberger

United States Military Academy — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.0kcitations68works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(7), HIV/AIDS drug development and treatment(6), Synthesis and Biological Evaluation(6), Synthesis of heterocyclic compounds(6), Protein Structure and Dynamics(4)

Publications68 total

Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency
Bioorganic & Medicinal Chemistry Letters·2015· 22 cited
Direct Evidence of 2-Cyano-2-Propoxy Radical Activity During AIBN-Based Oxidative Stress Testing in Acetonitrile–Water Solvent Systems
Journal of Pharmaceutical Sciences·2013· 15 cited
Cover Picture: Design and Synthesis of 2,3,5‐Substituted Imidazolidin‐4‐one Inhibitors of BACE‐1 (ChemMedChem 7/2007)
ChemMedChem·2007Open Access
Design and Synthesis of 2,3,5‐Substituted Imidazolidin‐4‐one Inhibitors of BACE‐1
ChemMedChem·2007· 38 cited
Asymmetric Addition Reactions of Grignard Reagents to Chiral 2‐Trifluoromethyl tert‐Butyl (Ellman) Sulfinimine—Ethanol Adducts.
ChemInform·2006
Asymmetric addition reactions of Grignard reagents to chiral 2-trifluoromethyl tert-butyl (Ellman) sulfinimine–ethanol adducts
Tetrahedron Letters·2006· 38 cited
CCDC 296065: Experimental Crystal Structure Determination
The Cambridge Structural Database·2006Open Access
CCDC 296066: Experimental Crystal Structure Determination
The Cambridge Structural Database·2006Open Access
Mechanism of the Solution Oxidation of Rofecoxib Under Alkaline Conditions
Pharmaceutical Research·2005· 12 cited
A novel oxidative degradation pathway of indomethacin under the stressing by hydrogen peroxide
Tetrahedron Letters·2005· 16 cited
Identification and quantitation of extractables from cellulose acetate butyrate (CAB) and estimation of their in vivo exposure levels
Journal of Pharmaceutical and Biomedical Analysis·2004· 5 cited
BIOACTIVATION OF THE 3-AMINO-6-CHLOROPYRAZINONE RING IN A THROMBIN INHIBITOR LEADS TO NOVEL DIHYDRO-IMIDAZOLE AND IMIDAZOLIDINE DERIVATIVES: STRUCTURES AND MECHANISM USING 13C-LABELS, MASS SPECTROMETRY, AND NMR
Drug Metabolism and Disposition·2003· 11 cited
PREPARATION, ISOLATION, AND CHARACTERIZATION OF DIMERIC DEGRADATION PRODUCTS OF THE 1β-METHYLCARBAPENEM ANTIBIOTIC, ERTAPENEM
Journal of Liquid Chromatography & Related Technologies·2001· 27 cited
Conformation of a novel tetrapeptide inhibitor NH<sub>2</sub>‐<scp>d</scp>‐Trp‐<scp>d</scp>‐Met‐Phe(<i>p</i>Cl)‐Gla‐NH<sub>2</sub>bound to farnesyl‐protein transferase
Journal of Peptide Research·1999· 7 citedOpen Access
Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase
Journal of Medicinal Chemistry·1999· 196 citedOpen Access
ChemInform Abstract: Complestatin to Chloropeptin I via a Quantitative Acid Catalyzed Rearrangement. Absolute Stereochemical Determination of Complestatin.
ChemInform·1998
Antibacterial Activity of Lonchocarpol A
Journal of Natural Products·1998· 27 cited
Complestatin to chloropeptin I via a quantitative acid catalyzed rearrangement. Absolute stereochemical determination of complestatin.
Tetrahedron Letters·1998· 29 cited
High Fatty Acid Content in Rabbit Serum Is Responsible for the Differentiation of Osteoblasts Into Adipocyte-like Cells
Journal of Bone and Mineral Research·1998· 207 citedOpen Access
Characterization of a Solid State Reaction Product from a Lyophilized Formulation of a Cyclic Heptapeptide. A Novel Example of an Excipient-Induced Oxidation
Pharmaceutical Research·1996· 45 cited
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Frequent Co-authors

Harri G. Ramjit(11), Michael J. Bogusky(6), Sándor Varga(5), Kamlesh P. Vyas(5), Suresh K. Balani(5), Keith M. Witherup(4), P H Kari(4), Byron H. Arison(4), Paul Anderson(3), Harold G. Selnick(3), Joseph P. Vacca(3), V M Garsky(3), Roger Freidinger(3), Daniel F. Veber(3), Carl J. Burke(3), C. Russell Middaugh(3), Adel M. Naylor(3), Carl F. Homnick(3), Paul A. Harmon(3), L R Kauffman(3)