J Hähnlein

Amsterdam University Medical Centers — Netherlands

Medicine · Health Sciences

9h-index290citations23works0.02yr avg
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Research Topics

Systemic Lupus Erythematosus Research(14), Rheumatoid Arthritis Research and Therapies(12), Monoclonal and Polyclonal Antibodies Research(11), T-cell and B-cell Immunology(9), Immunotherapy and Immune Responses(5)

Publications23 total

Increased Frequency of CD4+ Follicular Helper T and CD8+ Follicular T Cells in Human Lymph Node Biopsies during the Earliest Stages of Rheumatoid Arthritis
Cells·2022· 36 citedOpen Access
Increased frequency of CD4 <sup>+</sup> and CD8 <sup>+</sup> follicular helper T cells in human lymph node biopsies during the earliest stages of rheumatoid arthritis
2021· 1 citedOpen Access
Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis
International Journal of Molecular Sciences·2020· 12 citedOpen Access
Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis
Frontiers in Immunology·2019· 25 citedOpen Access
Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis
Arthritis Research & Therapy·2018· 33 citedOpen Access
O008 Altered lymph node stromal cells during the earliest phases of rheumatoid arthritis
Annals of the Rheumatic Diseases·2018Open Access
Distinctive expression of T cell guiding molecules in human autoimmune lymph node stromal cells upon TLR3 triggering
Scientific Reports·2018· 18 citedOpen Access
Human lymph node stromal cells and their role in rheumatoid arthritis
Data Archiving and Networked Services (DANS)·2018Open Access
Lymph node biopsy analysis reveals an altered immunoregulatory balance already during the at‐risk phase of autoantibody positive rheumatoid arthritis
European Journal of Immunology·2016· 34 citedOpen Access
Brief Report: Altered Innate Lymphoid Cell Subsets in Human Lymph Node Biopsy Specimens Obtained During the At‐Risk and Earliest Phases of Rheumatoid Arthritis
Arthritis & Rheumatology·2016· 61 citedOpen Access
Human lymph‐node CD8<sup>+</sup> T cells display an altered phenotype during systemic autoimmunity
Clinical & Translational Immunology·2016· 24 citedOpen Access
A3.06 Distinct expression pattern of peripheral tissue-restricted antigens in human LYMPH node stromal cells during the earliest phases of rheumatoid arthritis
Annals of the Rheumatic Diseases·2016
A1.20 Lymphoid tissue analyses in autoantibody positive individuals at risk for developing rheumatoid arthritis reveals an important role for CD8+ T cells during the earliest phases of autoimmunity
Annals of the Rheumatic Diseases·2015
A1.8 CD4+ T-helper cell subsets in lymph node biopsies and peripheral blood during the earliest phases of rheumatoid arthritis
Annals of the Rheumatic Diseases·2015
A6.9 Distinct expression of T-cell homing molecules in human autoimmune lymph node stromal cells upon TLR-3 triggering
Annals of the Rheumatic Diseases·2015
OP0256 Changes of Microrna Expression in Lymph Node Stromal Cells of Rheumatoid Arthritis Patients
Annals of the Rheumatic Diseases·2014
FRI0353 Human Lymph Node Stromal Cells Obtained from Rheumatoid Arthritis Patients as Well as from Healthy Individuals Express the Autoimmune Regulator Aire
Annals of the Rheumatic Diseases·2014
A1.32 An imbalance between inflammatory and regulatory T-cell subsets in LYMPH node biopsies during the earliest phases of rheumatoid arthritis
Annals of the Rheumatic Diseases·2014
A8.17 Expression of the autoimmune regulator aire in human lymph node stromal cells
Annals of the Rheumatic Diseases·2014· 1 cited
THU0111 T-Cell Subsets in Lymph Node Biopsies of Autoantibody Positive Subjects at Risk of Rheumatoid Arthritis (RA) and Early RA Patients
Annals of the Rheumatic Diseases·2013
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Frequent Co-authors

Lisa G. M. van Baarsen(15), Daniëlle M. Gerlag(12), Tamara H. Ramwadhdoebé(11), Mario Maas(11), Paul P. Tak(7), Paul P. Tak(7), K.I. Maijer(7), PP Tak(7), Johanna F. Semmelink(6), Ivy Y. Choi(6), TH Ramwadhdoebe(6), DM Gerlag(6), LGM van Baarsen(5), Teunis B. H. Geijtenbeek(4), Leonard J. van Boven(4), NAM Smits(4), Krijn P. van Lienden(3), Steffen Gay(3), Caroline Ospelt(3), Ferco H. Berger(3)