Ignacio Fajardo

Universidad de Málaga — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index911citations21works0.02yr avg
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Research Topics

Polyamine Metabolism and Applications(13), Mast cells and histamine(11), Food Allergy and Anaphylaxis Research(4), Coagulation, Bradykinin, Polyphosphates, and Angioedema(4), Amino Acid Enzymes and Metabolism(4)

Publications21 total

Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles
Journal of Chemical Education·2022Open Access
Evaluation of Histidine Decarboxylase (HDC) Activity and Human Histamine Receptor 3 (H3R) and HDC mRNA Levels
Methods in pharmacology and toxicology·2017
A novel role for antizyme inhibitor 2 as a regulator of serotonin and histamine biosynthesis and content in mouse mast cells
Amino Acids·2016· 13 cited
Conventional Matrices Loaded Onto a Graphene Layer Enhances MALDI-TOF/TOF Signal: Its Application to Improve Detection of Phosphorylated Peptides
Journal of the American Society for Mass Spectrometry·2015· 8 citedOpen Access
Nascent histamine induces α-synuclein and caspase-3 on human cells
Biochemical and Biophysical Research Communications·2014· 7 cited
Polyamines Are Present in Mast Cell Secretory Granules and Are Important for Granule Homeostasis
PLoS ONE·2010· 56 citedOpen Access
Polyamines affect histamine synthesis during early stages of IL‐3‐induced bone marrow cell differentiation
Journal of Cellular Biochemistry·2009· 18 citedOpen Access
The polyamine and histamine metabolic interplay in cancer and chronic inflammation
Current Opinion in Clinical Nutrition & Metabolic Care·2008· 23 cited
Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan
Journal of Allergy and Clinical Immunology·2008· 102 cited
Cathepsin B activates human trypsinogen 1 but not proelastase 2 or procarboxypeptidase B
Pancreatology·2006· 22 cited
A Key Role for Mast Cell Chymase in the Activation of Pro-matrix Metalloprotease-9 and Pro-matrix Metalloprotease-2
Journal of Biological Chemistry·2004· 313 citedOpen Access
The C-terminus of rat <scp>L</scp>-histidine decarboxylase specifically inhibits enzymic activity and disrupts pyridoxal phosphate-dependent interactions with <scp>L</scp>-histidine substrate analogues
Biochemical Journal·2004· 32 citedOpen Access
Increased Levels of Hypoxia-sensitive Proteins in Allergic Airway Inflammation
American Journal of Respiratory and Critical Care Medicine·2004· 88 cited
Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability
European Journal of Biochemistry·2003· 35 cited
Human Mast Cell β-Tryptase Is a Gelatinase
The Journal of Immunology·2003· 82 citedOpen Access
Formation of active monomers from tetrameric human beta-tryptase
Biochemical Journal·2003· 45 citedOpen Access
Effects of phorbol ester and dexamethasone treatment on histidine decarboxylase and ornithine decarboxylase in basophilic cells
Biochemical Pharmacology·2001· 32 cited
Histamine prevents polyamine accumulation in mouse C57.1 mast cell cultures
European Journal of Biochemistry·2001· 24 cited
An experiment on apoptosis induced by polyamine adducts produced in the presence of serum amine oxidase
Biochemical Education·2000· 2 cited
An experiment on apoptosis induced by polyamine adducts produced in the presence of serum amine oxidase
Biochemical Education·2000· 4 cited
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Frequent Co-authors

Francisca Sánchez‐Jiménez(13), José Luis Urdiales(11), Gunnar Pejler(7), Miguel Ángel Medina(7), Gianni García‐Faroldi(4), Magnus Åbrink(2), Carlos E. Rodríguez(2), Daniel Rodrı́guez-Agudo(2), Carlos Acosta‐Andrade(2), Ana R. Quesada(2), Elena Tchougounova(1), Anders Lundequist(1), Jan‐Olof Winberg(1), Maria Ringvall(1), Elin Rönnberg(1), Sara Wernersson(1), Annette Duelli(1), Frida Henningsson(1), Linda Svensson(1), Anders Bucht(1)