F C Gaeta

Amgen (United States) — United States

Medicine · Health Sciences

28h-index4.6kcitations44works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(11), Glycosylation and Glycoproteins Research(10), Immunotherapy and Immune Responses(8), Cell Adhesion Molecules Research(6), Carbohydrate Chemistry and Synthesis(6)

Publications44 total

Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
Proceedings of the National Academy of Sciences·2010· 195 cited
AV411 (Ibudilast) and AV1013 are non-competitive inhibitors of macrophage migration inhibitory factor: a novel induced-fit allosteric inhibition mechanism (133.11)
The Journal of Immunology·2010
Cross-species comparisons of the pharmacokinetics of ibudilast
Xenobiotica·2009· 32 cited
Cross-species comparisons of the pharmacokinetics of ibudilast
Xenobiotica·2009· 1 cited
ChemInform Abstract: An Improved Procedure for the Regiospecific Synthesis of Electron‐Deficient 4‐ and 6‐Substituted Isatins.
ChemInform·1998
An improved procedure for the regiospecific synthesis of electron deficient 4- and 6-substituted isatins
Tetrahedron Letters·1998· 23 cited
Ligand Interactions with E-Selectin. Identification of a New Binding Site for Recognition of <i>N</i>-Acyl Aromatic Glucosamine Substituents of Sialyl Lewis X
Journal of Medicinal Chemistry·1996· 36 citedOpen Access
Examination of the sialyl lewis X - calcium complex by electrospray mass spectrometry
Bioorganic & Medicinal Chemistry Letters·1994· 19 cited
Structure-Activity Relationships of Sialyl Lewis x-Containing Oligosaccharides. 1. Effect of Modifications of the Fucose Moiety
Journal of Medicinal Chemistry·1994· 82 citedOpen Access
Thrombin receptor peptide-mediated leukocyte rolling in rat mesenteric venules: roles of P-selectin and sialyl Lewis X
American Journal of Physiology-Heart and Circulatory Physiology·1994· 44 cited
Failure to demonstrate long-lived MHC saturation both in vitro and in vivo. Implications for therapeutic potential of MHC-blocking peptides.
The Journal of Immunology·1994· 57 citedOpen Access
Sialyl Lewisx-containing oligosaccharide attenuates myocardial reperfusion injury in cats.
Journal of Clinical Investigation·1994· 176 citedOpen Access
Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature.
Journal of Clinical Investigation·1994· 138 citedOpen Access
ChemInform Abstract: A New Multi‐Enzyme System for a One‐Pot Synthesis of Sialyl Oligosaccharides: Combined Use of β‐Galactosidase and α(2,6) ‐Sialyltransferase Coupled with Regeneration in situ of CMP‐Sialic Acid.
ChemInform·1993
HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions.
The Journal of Immunology·1993· 150 citedOpen Access
Peptide Stability in Drug Development. II. Effect of Single Amino Acid Substitution and Glycosylation on Peptide Reactivity in Human Serum
Pharmaceutical Research·1993· 183 cited
Ligand recognition by E-selectin: analysis of conformation and activity of synthetic monomeric and bivalent sialyl Lewis X analogs
Journal of the American Chemical Society·1993· 96 cited
Freezing adhesion molecules in a state of high-avidity binding blocks eosinophil migration.
The Journal of Experimental Medicine·1993· 135 citedOpen Access
A new multi-enzyme system for a one-pot synthesis of sialyl oligosaccharides: Combined use of β-galactosidase and α(26)-sialyltransferase coupled with regeneration in situ of CMP-sialic acid
Tetrahedron Letters·1993· 88 cited
MHC class II molecules bind indiscriminately self and non-self peptide homologs: effect on the immunogenicity of non-self peptides
International Immunology·1993· 14 cited
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Frequent Co-authors

Thomas Arrhenius(7), John Sidney(7), S M Colón(7), Alessandro Sette(5), Scott Southwood(5), H M Grey(5), Yoshitaka Ichikawa(5), James C. Paulson(4), Carla Oseroff(4), Michael F. Powell(4), Chi‐Huey Wong(4), Jeff Alexander(3), Donal M. O’Sullivan(3), M Wall(3), Kirk W. Johnson(3), Shawn DeFrees(3), Timothy P. Kogan(3), Howard M. Grey(2), Marika Guercio(2), Yoonsang Cho(2)