Chuan‐Chou Tu

Taichung Armed Forces General Hospital — Taiwan

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index755citations18works0.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(3), NF-κB Signaling Pathways(3), Nigella sativa pharmacological applications(3), Cell death mechanisms and regulation(2), Estrogen and related hormone effects(2)

Publications18 total

FOXC1 Regulation of miR-31-5p Confers Oxaliplatin Resistance by Targeting LATS2 in Colorectal Cancer
Cancers·2019· 78 citedOpen Access
Inhibition of Protein Phosphatase 1 Stimulates Noncanonical ER Stress eIF2α Activation to Enhance Fisetin-induced Chemosensitivity in HDAC Inhibitor-resistant Hepatocellular Carcinoma Cells
Cancers·2019· 22 citedOpen Access
CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT‐11‐resistant LoVo colon cancer cells via Gαi‐2 and Gαq/11
Journal of Cellular Physiology·2018· 63 cited
Overexpression of ZAKβ in human osteosarcoma cells enhances ZAKα expression, resulting in a synergistic apoptotic effect
Cell Biochemistry and Function·2018· 1 cited
Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo
Journal of Cellular Physiology·2018· 52 cited
Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis
Journal of Cellular Physiology·2017· 165 cited
Doxorubicin induces <scp>ZAK</scp>α overexpression with a subsequent enhancement of apoptosis and attenuation of survivability in human osteosarcoma cells
Environmental Toxicology·2017· 3 cited
Erratum to: Hypoxia Augments Increased HIF-1a and Reduced Survival Protein p-Akt in Gelsolin (GSN)-Dependent Cardiomyoblast Cell Apoptosis
Cell Biochemistry and Biophysics·2017· 2 citedOpen Access
Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation
World Journal of Gastroenterology·2017· 73 citedOpen Access
E2/ERβ Inhibits PPARα to Regulate Cell-Proliferation and Enhance Apoptosis in Hep3B-Hepatocellular Carcinoma
Pathology & Oncology Research·2016· 9 cited
Inhibition of NF‐κB and metastasis in irinotecan (CPT‐11)‐resistant LoVo colon cancer cells by thymoquinone via JNK and p38
Environmental Toxicology·2016· 54 cited
Estrogen and ERα enhanced β‐catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK‐3β and β‐TrCP expression
Environmental Toxicology·2016· 12 cited
Taiwanin C selectively inhibits arecoline and 4‐NQO‐induced oral cancer cell proliferation via ERK1/2 inactivation
Environmental Toxicology·2015· 9 citedOpen Access
Helioxanthin suppresses the cross talk of COX-2/PGE2 and EGFR/ERK pathway to inhibit Arecoline-induced Oral Cancer Cell (T28) proliferation and blocks tumor growth in xenografted nude mice
Environmental Toxicology·2015· 16 cited
Thymoquinone Induces Caspase-Independent, Autophagic Cell Death in CPT-11-Resistant LoVo Colon Cancer via Mitochondrial Dysfunction and Activation of JNK and p38
Journal of Agricultural and Food Chemistry·2015· 88 cited
Apicidin-Resistant HA22T Hepatocellular Carcinoma Cells strongly activated the Wnt/β-Catenin Signaling Pathway and MMP-2 Expression via the IGF-IR/PI3K/Akt Signaling Pathway Enhancing Cell Metastatic Effect
Bioscience Biotechnology and Biochemistry·2013· 27 cited
Estrogen receptor α (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins
Journal of Molecular Endocrinology·2013· 40 citedOpen Access
ZAK inhibits human lung cancer cell growth via ERK and JNK activation in an AP‐1‐dependent manner
Cancer Science·2010· 41 citedOpen Access

Frequent Co-authors

Chih‐Yang Huang(17), Wei‐Wen Kuo(11), Ming‐Cheng Chen(9), Vijaya Padma Viswanadha(9), Hsi‐Hsien Hsu(8), Hsi-Hsien Hsu(8), Yueh‐Min Lin(6), Tsung‐Jung Ho(6), Ming-Cheng Chen(5), Yueh-Min Lin(4), Bharath Kumar Velmurugan(4), Cecilia Hsuan Day(3), N. Lee(3), Jaw‐Ji Yang(3), Rathinasamy Baskaran(2), Hui-Nung Shih(2), Po‐Hsiang Liao(2), Ray‐Jade Chen(2), Fuu‐Jen Tsai(2), You-Liang Hsieh(2)