F. Merlin Bumpus

National Institutes of Health — United States

Medicine · Health Sciences

47h-index9.6kcitations192works0.02yr avg
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Research Topics

Renin-Angiotensin System Studies(57), Chemical Synthesis and Analysis(47), Receptor Mechanisms and Signaling(41), Hormonal Regulation and Hypertension(37), Enzyme function and inhibition(17)

Publications192 total

Past American Peptide Symposia/International Peptide Symposia
Biopolymers·2005Open Access
Measurement of angiotensin I converting enzyme inhibition in the heart.
Circulation Research·1993· 71 cited
Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart.
Journal of Clinical Investigation·1993· 397 citedOpen Access
Effects of angiotensin I of the american bullfrog Rana catesbeiana on amphibian tissues
Comparative Biochemistry and Physiology Part A Physiology·1993· 2 cited
A novel angiotensin II-forming pathway in the human heart
Journal of Molecular and Cellular Cardiology·1992
Angiotensin I and II. Some early observations made at the Cleveland Clinic Foundation and recent discoveries relative to angiotensin II formation in human heart.
Hypertension·1991· 12 cited
Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart.
Journal of Biological Chemistry·1991· 127 citedOpen Access
Cloning of the gene and cDNA for human heart chymase.
Journal of Biological Chemistry·1991· 151 citedOpen Access
Nomenclature for angiotensin receptors. A report of the Nomenclature Committee of the Council for High Blood Pressure Research.
Hypertension·1991· 388 cited
Biochemical Properties of the Ovarian Granulosa Cell Type 2-Angiotensin II Receptor*
Endocrinology·1991· 217 cited
Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart.
Journal of Biological Chemistry·1990· 879 citedOpen Access
Characterization of Angiotensin I-Converting Enzyme (ACE)-Containing Follicles in the Rat Ovary during the Estrous Cycle and Effects of ACE Inhibitor on Ovulation*
Endocrinology·1990· 47 cited
Angiotensins and the failing heart. Enhanced positive inotropic response to angiotensin I in cardiomyopathic hamster heart in the presence of captopril.
Circulation Research·1990· 78 citedOpen Access
Angiotensin II-forming pathways in normal and failing human hearts.
Circulation Research·1990· 580 citedOpen Access
Angiotensin II: Does It Have a Direct Obligate Role in Ovulation?
Science·1989· 46 cited
Angiotensin II Receptors in Normal and Failing Human Hearts*
The Journal of Clinical Endocrinology & Metabolism·1989· 151 cited
Rat Ovarian Renin: Characterization and Changes during the Estrous Cycle*
Endocrinology·1988· 47 cited
Evidence for extracellular, but not intracellular, generation of angiotensin II in the rat adrenal zona glomerulosa.
Proceedings of the National Academy of Sciences·1988· 43 citedOpen Access
Regulation of angiotensin II receptors in cultured rat ovarian granulosa cells by follicle-stimulating hormone and angiotensin II.
Journal of Biological Chemistry·1988· 55 citedOpen Access
Evidence for Selective Expression of Angiotensin II Receptors on Atretic Follicles in the Rat Ovary: An Autoradiographic Study*
Endocrinology·1988· 93 cited
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Frequent Co-authors

Ahsan Husain(17), Robert R. Smeby(13), M. C. Khosla(9), H Urata(7), Philip A. Khairallah(7), Irvine H. Page(7), Ayaka Kinoshita(5), Robert C. Tarazi(5), S Sen(5), Anthony G. Pucell(5), Bernadine Healy(3), Subha Sen(3), M J Peach(3), Adil Daud(3), Serge Fermandjian(3), K S Misono(2), Robert W. Stewart(2), Hans Peter Schwarz(2), M. M. Hall(2), Kikuo Arakawa(2)