Lucia Negri

Neuroscience · Life Sciences

43h-index5.7kcitations191works4.82yr avg
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Research Topics

Neuropeptides and Animal Physiology(88), Receptor Mechanisms and Signaling(49), Pharmacological Receptor Mechanisms and Effects(31), Hypothalamic control of reproductive hormones(26), Pain Mechanisms and Treatments(25)

Publications181 total

HPLC Purification of TRPM8 and Experimental Confirmation of Its Cholesterol Affinity on Synthetic Lipid Raft-like Models
MDPI (MDPI AG)·2026Open Access
Optimization of the Operant Silent Gap-in-Noise Detection Paradigm in Humans
Journal of Integrative Neuroscience·2024· 1 citedOpen Access
The prokineticin receptor antagonist PC1 rescues memory impairment induced by β amyloid administration through the modulation of prokineticin system
Neuropharmacology·2019· 20 cited
In vitro and in vivo Pharmacological Activities of 14-O-Phenylpropyloxymorphone, a Potent Mixed Mu/Delta/Kappa-Opioid Receptor Agonist With Reduced Constipation in Mice
Frontiers in Pharmacology·2018· 14 citedOpen Access
PK2β ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through PKR1 receptor
Neuropeptides·2018· 23 cited
Targeting the Prokineticin System to Control Chronic Pain and Inflammation
Current Medicinal Chemistry·2018· 28 cited
The Prokineticins: Neuromodulators and Mediators of Inflammation and Myeloid Cell-Dependent Angiogenesis
Physiological Reviews·2018· 91 citedOpen Access
The Involvement of Post-Translational Modifications in Alzheimer's Disease
Current Alzheimer Research·2017· 105 cited
Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease
Neuropharmacology·2016· 24 cited
Abstract 1437: Relationship of G-CSF related bone pain (BP) with Bv8/PK2 expression in breast cancer (BC) patients (pts) treated with FEC100 adjuvant chemotherapy (CT)
Cancer Research·2016
Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro
Neuropharmacology·2016· 44 cited
The prokineticin Bv8 sensitizes cutaneous terminals of female mice to heat
European Journal of Pain·2016· 5 citedOpen Access
Antagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of Diabetes
PLoS ONE·2016· 48 citedOpen Access
Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity
Scientific Reports·2015· 41 citedOpen Access
Critical role for prokineticin 2 in CNS autoimmunity
Neurology Neuroimmunology & Neuroinflammation·2015· 35 citedOpen Access
Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization
International Journal of Pharmaceutical Sciences and Research·2015· 2 citedOpen Access
Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model
BioMed Research International·2015· 42 citedOpen Access
Mhamad Abou-Hamdan,
2015
PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice
Pharmacological Research·2014· 42 cited
ChemInform Abstract: A New Convenient Synthetic Method and Preliminary Pharmacological Characterization of Triazinediones as Prokineticin Receptor Antagonists.
ChemInform·2014
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Frequent Co-authors

Pietro Melchiorri(25), Roberta Lattanzi(21), Elisa Giannini(13), V. Erspamer(12), Cinzia Severini(9), G. Falconieri Erspamer(9), Gianfranco Balboni(9), Donatella Barra(7), Severo Salvadori(7), Paola Sacerdote(6), Rita Corsi(5), V. I. Marconi(5), Daniela Maftei(5), Mariantonella Colucci(4), Silvia Franchi(4), Giuliana Falconieri–Erspamer(3), Maurizio Simmaco(3), Günther Kreil(3), Giuseppina Mignogna(3), Hui Tian(3)