Heather S. Bonner

Hospital of the University of Pennsylvania — United States

Medicine · Health Sciences

17h-index1.6kcitations26works0.02yr avg
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Research Topics

Effects of Radiation Exposure(7), Advanced Radiotherapy Techniques(4), Radiation Therapy and Dosimetry(4), Lymphoma Diagnosis and Treatment(3), Acute Myeloid Leukemia Research(3)

Publications26 total

Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
Drug Metabolism and Disposition·2002· 21 cited
A pilot study of topical intrarectal application of amifostine for prevention of late radiation rectal injury
International Journal of Radiation Oncology*Biology*Physics·2002· 48 cited
New Dosing Regimens for Amifostine: A Pilot Study to Compare the Relative Bioavailability of Oral and Subcutaneous Administration with Intravenous Infusion
The Journal of Clinical Pharmacology·2002· 48 cited
Measurement of both protein-bound and total S-2-(3-aminopropylamino)ethanethiol (WR-1065) in blood by high-performance liquid chromatography
Journal of Chromatography B Biomedical Sciences and Applications·2000· 14 cited
ANALYSIS OF PROTEIN-BOUND AND TOTAL S-2-(3-AMINOPROPYLAMINO)ETHANETHIOL (WR-1065) IN BLOOD BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC).
Therapeutic Drug Monitoring·1999
Pharmacokinetics of amifostine: effects of dose and method of administration.
PubMed·1999· 57 cited
A Phase II Trial and Pharmacokinetic Analysis of 96-Hour Infusional Paclitaxel in Patients With Metastatic Colorectal Cancer
American Journal of Clinical Oncology·1998· 14 cited
Pharmacokinetic profile of amifostine.
PubMed·1996· 43 cited
158 A PHARMACOKINETIC STUDY OF PACLITAXEL IN PATIENTS WITH METASTATIC COLORECTAL CANCER
Therapeutic Drug Monitoring·1995
Topical Application of WR-2721 Achieves High Concentrations in the Rectal Wall
Radiation Research·1995· 25 cited
Metabolic pathways of WR-2721 (ethyol, amifostine) in the BALB/c mouse.
PubMed·1994· 54 cited
Metabolic pathways of WR-2721 (ethyol, amifostine) in the BALB/c mouse.
Drug Metabolism and Disposition·1994· 8 cited
The Use of Concentration Measurements of Parent Drug and Metabolites During Clinical Trials
Therapeutic Drug Monitoring·1993· 6 cited
Comparison of chlorambucil and prednisone versus cyclophosphamide, vincristine, and prednisone as initial treatment for chronic lymphocytic leukemia: long-term follow-up of an Eastern Cooperative Oncology Group randomized clinical trial.
Journal of Clinical Oncology·1991· 130 cited
Pharmacokinetics of WR-2721
Pharmacology & Therapeutics·1988· 79 cited
Mediastinal Involvement in Adults with Lymphoblastic Lymphoma
Acta Radiologica·1987· 3 cited
Detection and Measurement of the Disulfide WR33278 [NH<sub>2</sub>(CH<sub>2</sub>)<sub>3</sub>NHCH<sub>2</sub>CH<sub>2</sub>S-]<sub>2</sub>in Blood and Tissues
Journal of Liquid Chromatography·1987· 8 cited
Human pharmacokinetics of WR-2721
International Journal of Radiation Oncology*Biology*Physics·1986· 93 cited
Hydrolysis of S-2-(3-aminopropylamino)ethylphosphorothioate (WR-2721)
Biochemical Pharmacology·1986· 17 cited
Measurement of S-2-(3-Aminopropylamino)ethanethiol (WR1065) in Blood and Tissues
Journal of Liquid Chromatography·1986· 27 cited
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Frequent Co-authors

Yi‐Ju Li(10), Pilhan Kim(4), Andrew T. Turrisi(4), A.Lorraine Norfleet(4), Leslie M. Shaw(4), Donna Glover(3), Morton M. Kligerman(3), J. J. Mazza(2), John M. Bennett(2), John H. Glick(2), Ronald Lieberman(2), D Q Brown(2), David J. Vaughn(2), James C. Arseneau(1), Robert W. Sponzo(1), David L. Levin(1), L Schnipper(1), Robert C. Young(1), George P. Canellos(1), R. E. Johnson(1)