David R. Gretch

University of Washington — United States

Medicine · Health Sciences

59h-index15.8kcitations159works0.02yr avg
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Research Topics

Hepatitis C virus research(136), Liver Disease Diagnosis and Treatment(79), Hepatitis B Virus Studies(74), Systemic Lupus Erythematosus Research(25), HIV/AIDS drug development and treatment(14)

Publications159 total

Fibrosing Cholestatic Hepatitis C After Hematopoietic Cell Transplantation
The American Journal of Surgical Pathology·2014· 30 cited
The stability of secreted, acid-labile H77/JFH-1 hepatitis C virus (HCV) particles is altered by patient isolate genotype 1a p7 sequences
Virology·2013· 15 citedOpen Access
Editorial Commentary: Advocating the Concept of GB Virus C Biotherapy Against AIDS
Clinical Infectious Diseases·2012· 18 citedOpen Access
Genetic and functional heterogeneity of the hepatitis C virus p7 ion channel during natural chronic infection
Virology·2011· 14 cited
Genetic Diversity of Near Genome-Wide Hepatitis C Virus Sequences during Chronic Infection: Evidence for Protein Structural Conservation Over Time
PLoS ONE·2011· 29 citedOpen Access
Impact of CD4+ T-cell count on the performance of non-invasive fibrosis markers in HIV-HCV patients: authors’ reply
Alimentary Pharmacology & Therapeutics·2011Open Access
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity
Journal of Clinical Investigation·2011· 14 citedOpen Access
Use of the AST to platelet ratio index in HCV/HIV co‐infected patients
Alimentary Pharmacology & Therapeutics·2011· 33 citedOpen Access
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity
Journal of Clinical Investigation·2010· 297 citedOpen Access
Genetic diversity of hepatitis C virus predicts recurrent disease after liver transplantation
Virology·2010· 13 citedOpen Access
Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1
Journal of Gastroenterology and Hepatology·2010· 131 citedOpen Access
CLINICAL—LIVER, PANCREAS, AND BILIARY TRACT Adverse Outcomes in Alaska Natives Who Recovered From or Have Chronic Hepatitis C Infection
2010
Factors Associated with the Progression of Fibrosis on Liver Biopsy in Alaska Native and American Indian Persons with Chronic Hepatitis C
Canadian Journal of Gastroenterology·2010· 13 citedOpen Access
Adverse Outcomes in Alaska Natives Who Recovered From or Have Chronic Hepatitis C Infection
Gastroenterology·2009· 49 citedOpen Access
Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4 <sup>+</sup> and CD8 <sup>+</sup> T Cells
Journal of Virology·2009· 425 citedOpen Access
Variants in interferon‐alpha pathway genes and response to pegylated interferon‐Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long‐term treatment against cirrhosis trial†‡
Hepatology·2009· 80 citedOpen Access
Interpretation of positive transcription-mediated amplification test results from polymerase chain reaction–negative samples obtained after treatment of chronic hepatitis C
Hepatology·2008· 26 citedOpen Access
Investigation of Putative Multisubtype Hepatitis C Virus Infections In Vivo by Heteroduplex Mobility Analysis of Core/Envelope Subgenomes
Journal of Virology·2008· 17 citedOpen Access
Hepatitis C virus envelope glycoprotein co-evolutionary dynamics during chronic hepatitis C
Virology·2008· 16 citedOpen Access
Clinical significance of elevated alpha‐fetoprotein in Alaskan Native patients with chronic hepatitis C
Journal of Viral Hepatitis·2007· 35 cited
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Frequent Co-authors

Stephen J. Polyak(13), Robert L. Carithers(10), Lawrence Corey(8), Hugo R. Rosen(6), Marc G. Ghany(6), Daniel G. Sullivan(6), Adrian M. Di Bisceglie(5), James D. Perkins(5), Charles E. Alpers(4), Richard A. Willson(4), Herbert L. Bonkovsky(4), Gregory T. Everson(4), Timothy R. Morgan(4), Robert J. Fontana(4), Richard J. Johnson(3), Hideaki Yamabe(3), Jaime Hart(3), Mark H. Wener(3), Michael Gale(3), Brian J. McMahon(3)