Lars Knutson

South Dakota State University — United States

Medicine · Health Sciences

31h-index3.5kcitations85works0.02yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(27), Helicobacter pylori-related gastroenterology studies(15), Gastrointestinal motility and disorders(10), Drug Solubulity and Delivery Systems(9), Pharmacogenetics and Drug Metabolism(9)

Publications85 total

Author Reply to Peer Reviews of IFT20 regulates lymphatic endothelial cell-cell junctions via endocytic trafficking of VE-cadherin
2025
IFT20 regulates lymphatic endothelial cell-cell junctions via endocytic trafficking of VE-cadherin
2025Open Access
Combined in Vitro–in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor
Molecular Pharmaceutics·2013· 15 cited
Effects of Ketoconazole on the In Vivo Biotransformation and Hepatobiliary Transport of the Thrombin Inhibitor AZD0837 in Pigs
Drug Metabolism and Disposition·2010· 8 cited
Biliary Excretion of Ximelagatran and Its Metabolites and the Influence of Erythromycin Following Intraintestinal Administration to Healthy Volunteers
The Journal of Clinical Pharmacology·2010· 4 cited
Gastrointestinal metabolism of a vegetable-oil emulsion in healthy subjects
American Journal of Clinical Nutrition·2010· 32 cited
Effect of a Single Gemfibrozil Dose on the Pharmacokinetics of Rosuvastatin in Bile and Plasma in Healthy Volunteers
The Journal of Clinical Pharmacology·2010· 22 cited
In vivo studies of the biliary excretion of the oral thrombin inhibitor AZD0837 and its pharmacokinetic interaction with ketoconazole in humans
2010· 1 cited
Enterohepatic Disposition of Rosuvastatin in Pigs and the Impact of Concomitant Dosing with Cyclosporine and Gemfibrozil
Drug Metabolism and Disposition·2009· 30 cited
Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
Drug Metabolism and Disposition·2009· 16 cited
Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Drug Metabolism and Disposition·2009· 22 cited
Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver
2009
Identification of hydroxylated and glucuronidated metabolites of finasteride in human bile and urine
2009
The hepatobiliary disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine.
2009
The effect of gemfibrozil on the biliary excretion of rosuvastatin in pig and man
2009
The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men
European Journal of Pharmaceutical Sciences·2008· 37 cited
Intestinal and Hepatobiliary Transport of Ximelagatran and Its Metabolites in Pigs
Drug Metabolism and Disposition·2008· 20 cited
Improved understanding of the effect of food on drug absorption and bioavailability for lipophilic compounds using an intestinal pig perfusion model
European Journal of Pharmaceutical Sciences·2008· 27 cited
The effect of St John’s Wort treatment on finasteride metabolism and identification of new finasteride metabolites in humans
2008
Intestinal and liver CYP3A4-mediated metabolism of R/S-verapamil in pigs
2008
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Frequent Co-authors

Hans Lennernäs(26), Roger Hällgren(16), Tina W. Knutson(10), Örjan Ahrenstedt(7), Mikael Hedeland(7), Ulf Bondesson(7), Patrik Forsell(6), Bertil Abrahamsson(5), Bo Odlind(5), Ebba Bergman(5), Eva Persson(4), A Dannaeus(4), Gunnar Flemström(4), Anders Lindahl(3), Rikard Sandström(3), Bengt Lavö(3), Bengt Gerdin(3), Anna Lundahl(3), Ulf Bengtsson(3), S. Ahlstedt(3)