Jane Hu

Princeton University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index4.4kcitations93works9.22yr avg
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Research Topics

Retinal Development and Disorders(40), Retinal Diseases and Treatments(30), Retinoids in leukemia and cellular processes(12), Photoreceptor and optogenetics research(7), Connexins and lens biology(6)

Publications93 total

Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12
Cell Reports·2025· 2 citedOpen Access
Suppress or Not to Suppress … CRAFT It: A Targeted Metabolomics Case Study Extracting Essential Biomarker Signals Directly from the Full 1H NMR Spectra of Horse Serum Samples
Metabolites·2025Open Access
Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12
2024· 2 citedOpen Access
Impaired cathepsin D in retinal pigment epithelium cells mediates Stargardt disease pathogenesis
The FASEB Journal·2024· 8 citedOpen Access
CAR-T cell therapy targeting surface expression of TYRP1 to treat cutaneous and rare melanoma subtypes
Nature Communications·2024· 43 citedOpen Access
Chandelier retroillumination-assisted cataract surgery in two cases of congenital aniridia with severe aniridia-associated keratopathy: case series
Therapeutic Advances in Ophthalmology·2024Open Access
Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration
Cells·2022· 23 citedOpen Access
The Post-American Surreal
Dissent·2022
Assessing Variant Causality and Severity Using Retinal Pigment Epithelial Cells Derived from Stargardt Disease Patients
Translational Vision Science & Technology·2022· 9 citedOpen Access
Ang Lee's Tears: Digital Global Melodrama in The Wedding Banquet, Hulk, and Gemini Man
Verge Studies in Global Asias·2021· 1 cited
MeCP2-mediated mitochondrial impairment evidenced in Stargardt disease
Investigative Ophthalmology & Visual Science·2021Open Access
Membrane attack complex induces RPE cell death in Stargardt Disease
Investigative Ophthalmology & Visual Science·2021· 1 citedOpen Access
Cathepsin D deficiency in RPE cells mediates Stargardt Disease pathogenesis
Investigative Ophthalmology & Visual Science·2021· 1 citedOpen Access
Evidence of complement dysregulation in outer retina of Stargardt disease donor eyes
Redox Biology·2020· 22 citedOpen Access
Geographic Atrophy: Confocal Scanning Laser Ophthalmoscopy, Histology, and Inflammation in the Region of Expanding Lesions
Investigative Ophthalmology & Visual Science·2020· 39 citedOpen Access
Complement Dysregulation is Evidenced in iPSC-derived RPE Cells from Stargardt Disease patients
Investigative Ophthalmology & Visual Science·2020· 2 citedOpen Access
Regulatory mechanism for the transmembrane receptor that mediates bidirectional vitamin A transport
Proceedings of the National Academy of Sciences·2020· 34 citedOpen Access
Disease mechanisms elucidated by genetic regulation of human RPE gene expression
Investigative Ophthalmology & Visual Science·2019Open Access
Reduced expression of “normal” ABCA4 alleles in iPS-derived RPE cells from Stargardt Disease patients
Investigative Ophthalmology & Visual Science·2019Open Access
Retinoid recycling is impaired in Stargardt iPSC-derived RPE
Investigative Ophthalmology & Visual Science·2019Open Access
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Frequent Co-authors

Dean Bok(40), Roxana A. Radu(16), Gabriel H. Travis(8), Marcia Lloyd(6), Zhichun Jiang(5), Minghao Jin(5), Songhua Li(5), Joe G. Hollyfield(5), Monte J. Radeke(4), Ron P. Gallemore(4), Vera L. Bonilha(4), Lincoln V. Johnson(3), Steven Nusinowitz(3), Nicolás G. Bazán(3), Enrique Rodríguez-Boulan(3), Donald A. Frambach(3), Samuel G. Jacobson(3), Michael B. Gorin(3), Anna Matynia(3), Riki Kawaguchi(2)