W. Pangborn

Hauptman-Woodward Medical Research Institute — United States

Materials Science · Physical Sciences

16h-index1.9kcitations63works0.02yr avg
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Research Topics

Enzyme Structure and Function(9), Lipid Membrane Structure and Behavior(5), Pneumocystis jirovecii pneumonia detection and treatment(5), Biochemical and Molecular Research(5), DNA and Nucleic Acid Chemistry(4)

Publications63 total

Structure of gramicidin D–RbCl complex at atomic resolution from low-temperature synchrotron data: interactions of double-stranded gramicidin channel contents and cations with channel wall
Acta Crystallographica Section D Biological Crystallography·2005· 12 cited
Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH
Acta Crystallographica Section D Biological Crystallography·2005· 106 cited
A New Crystal Form of the Fab Fragment of a Monoclonal Antibody to Human Interleukin-2: The Three-Dimensional Structure at 2.7 Å Resolution
Russian Journal of Bioorganic Chemistry·2004· 2 cited
Ion channels in crystals of gramicidin D complex with RbCl. Atomic resolution low-temperature synchrotron X-ray data
Acta Crystallographica Section A Foundations of Crystallography·2004· 5 citedOpen Access
Structure determination of tetrahydroquinazoline antifolates in complex with human and<i>Pneumocystis carinii</i>dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry
Acta Crystallographica Section D Biological Crystallography·2004· 25 cited
Fab (LNKB-2) of monoclonal antibody to Human Interleukin-2, crystal structure
2004
Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry
2004· 1 cited
Structure of Human Placental Estrone/DHEA Sulfatase
2003
T6 Human Insulin at 1.0 A Resolution
2002
Three-dimensional structure of the Arg32His mutant of the human tumor necrosis factor determined at 2.5 Å resolution from X-ray data for a twin crystal
Crystallography Reports·2002
1.3 A STRUCTURE OF T3R3 HUMAN INSULIN AT 100 K
2000
ACETYLXYLAN ESTERASE AT 0.90 ANGSTROM RESOLUTION
2000
The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 in two crystal forms at 2.2 and 2.9 Å resolution
Russian Journal of Bioorganic Chemistry·2000· 6 cited
Novel Ion Coordination in Gramicidin, a Membrane Channel
Acta Crystallographica Section A Foundations of Crystallography·2000
T<sub>6</sub>and T<sub>3</sub>R<sub>3</sub>Human Insulin at Atomic Resolution
Acta Crystallographica Section A Foundations of Crystallography·2000Open Access
[Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms].
PubMed·2000· 9 cited
The structure of the resorcinol/insulin R6 hexamer
2000
Structure of the monoclinic form of the M-cresol/insulin R6 hexamer
2000· 6 cited
Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer
2000
The conducting form of gramicidin A is a right-handed double-stranded double helix
Proceedings of the National Academy of Sciences·1998· 125 citedOpen Access
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Frequent Co-authors

Vivian Cody(15), J.R. Luft(11), D. A. Langs(8), William L. Duax(8), В. З. Плетнев(8), Nikolai Galitsky(6), Aleem Gangjee(6), W. L. Duax(6), Sherry F. Queener(5), Joseph R. Luft(5), Brian M. Burkhart(4), Raymond L. Blakley(4), Debashis Ghosh(4), I. N. Tsygannik(4), George Davey Smith(4), Andrzej Wojtczak(3), Sheng‐Xiang Lin(3), Douglas L. Dorset(3), Z. Wawrzak(3), Mary Erman(3)