Leslie R. Adrien

Northwell Health — United States

Medicine · Health Sciences

9h-index804citations34works2.02yr avg
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Research Topics

Head and Neck Cancer Studies(13), Alzheimer's disease research and treatments(12), Cancer-related molecular mechanisms research(10), Neuroscience and Neuropharmacology Research(6), Epigenetics and DNA Methylation(4)

Publications34 total

Therapeutic Treatment With <scp>OLX</scp>‐07010 Inhibited Tau Aggregation and Ameliorated Motor Deficits in an Aged Mouse Model of Tauopathy
Journal of Neurochemistry·2025· 2 citedOpen Access
Small molecule inhibitor of tau self-association in a mouse model of tauopathy: A preventive study in P301L tau JNPL3 mice
PLoS ONE·2023· 8 citedOpen Access
The Impact of Muscarinic Antagonism on Psychosis-Relevant Behaviors and Striatal [11C] Raclopride Binding in Tau Mouse Models of Alzheimer’s Disease
Biomedicines·2023· 3 citedOpen Access
Data from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 6 and Figure from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 1 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 1 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 4 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 4 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 2 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 3 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Data from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 5 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 3 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 6 and Figure from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 2 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Supplementary Table 5 from Unique DNA Methylation Loci Distinguish Anatomic Site and HPV Status in Head and Neck Squamous Cell Carcinoma
2023Open Access
Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy
Molecular Medicine·2022· 5 citedOpen Access
The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT– and rTg(P301L)4510 mouse models of Alzheimer's disease
Alzheimer s & Dementia Translational Research & Clinical Interventions·2022· 6 citedOpen Access
<i>In vivo</i> validation of therapeutic efficacy of a small molecule lead targeting tau self‐association in JNPL3 mice
Alzheimer s & Dementia·2021
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Frequent Co-authors

Nicolas F. Schlecht(18), Michael B. Prystowsky(18), Thomas J. Belbin(18), Roberto A. Lleras(17), Richard V. Smith(17), Geoffrey Childs(16), Robert D. Burk(15), Thomas M. Harris(12), Peter Davies(11), Heidy Jimenez(11), Jeremy Koppel(8), Eliot J. Davidowitz(7), James G. Moe(7), Patricia López(5), Adam Wolin(5), John Eun(5), Philippe Marambaud(4), Eric H. Chang(4), Thomas M. Harris(3), Valérie Vingtdeux(2)