Elaine Irving

Age UK — United Kingdom

Neuroscience · Life Sciences

25h-index3.4kcitations58works0.02yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(14), Alzheimer's disease research and treatments(12), Neuroscience and Neuropharmacology Research(10), Health Systems, Economic Evaluations, Quality of Life(8), Neurogenesis and neuroplasticity mechanisms(7)

Publications58 total

The GetReal Trial Tool: design, assess and discuss clinical drug trials in light of Real World Evidence generation
Journal of Clinical Epidemiology·2021· 8 citedOpen Access
INTREPID: single-<i>versus</i>multiple-inhaler triple therapy for COPD in usual clinical practice
ERJ Open Research·2021· 67 citedOpen Access
Patient and healthcare professional experiences of the Salford Lung Studies: qualitative insights for future effectiveness trials
Trials·2020· 2 citedOpen Access
Late changes in blood–brain barrier permeability in a rat tMCAO model of stroke detected by gadolinium-enhanced MRI
Neurological Research·2020· 10 cited
Clinical effectiveness of once-daily fluticasone furoate/umeclidinium/vilanterol in usual practice: the COPD INTREPID study design
ERJ Open Research·2019· 15 citedOpen Access
Challenges in pragmatic trials: selection and inclusion of usual care sites.
Bern Open Repository and Information System (University of Bern)·2017· 19 citedOpen Access
Series: Pragmatic trials and real world evidence: Paper 1. Introduction
Journal of Clinical Epidemiology·2017· 221 citedOpen Access
Series: Pragmatic trials and real world evidence: Paper 2. Setting, sites, and investigator selection
Journal of Clinical Epidemiology·2017· 41 citedOpen Access
Series: Pragmatic trials and real world evidence: Paper 3. Patient selection challenges and consequences
Journal of Clinical Epidemiology·2017· 81 citedOpen Access
Series: Pragmatic trials and real world evidence: Paper 7. Safety, quality and monitoring
Journal of Clinical Epidemiology·2017· 25 citedOpen Access
Pragmatic trial design elements showed a different impact on trial interpretation and feasibility than explanatory elements
Journal of Clinical Epidemiology·2016· 14 cited
GSK249320, A Monoclonal Antibody Against the Axon Outgrowth Inhibition Molecule Myelin-Associated Glycoprotein, Improves Outcome of Rodents with Experimental Stroke
Journal of Neurology and Experimental Neuroscience·2016· 15 citedOpen Access
Rosiglitazone enhances learning, place cell activity, and synaptic plasticity in middle-aged rats
Neurobiology of Aging·2011· 36 cited
Disease Tracking Markers for Alzheimer's Disease at the Prodromal (MCI) Stage
Journal of Alzheimer s Disease·2011· 138 cited
P2‐007: Cerebral structural changes in APP/PS1 mice: A MRI longitudinal study
Alzheimer s & Dementia·2011
P2‐003: Longitudinal magnetic resonance spectroscopy analysis of APP/PS1 transgenic mice
Alzheimer s & Dementia·2011Open Access
P1‐047: Memantine reverses cognitive deficits induced by total sleep deprivation in O. degus
Alzheimer s & Dementia·2011
Enrichment through biomarkers in clinical trials of Alzheimer's drugs in patients with mild cognitive impairment
Neurobiology of Aging·2010· 52 cited
Clinical Trials of Alzheimer’s Drugs in Patients with Mild Cognitive Impairment: Enrichment of True Alzheimer’s Cases through Disease Markers
2010
Protection against Aβ-mediated rapid disruption of synaptic plasticity and memory by memantine
Neurobiology of Aging·2009· 67 cited
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Frequent Co-authors

Andrew A. Parsons(12), Frank C. Barone(6), Sally Worsley(6), David Virley(5), Jeffrey J. Legos(5), Rolf H. H. Groenwold(5), Diederick E. Grobbee(5), Neil Upton(5), A. Jacqueline Hunter(4), Deborah Dewar(4), Katrien Oude Rengerink(4), Sarah J. Hadingham(3), N. Upton(3), A. Jackie Hunter(3), Joseph A. Erhardt(3), Eliot H. Ohlstein(3), Mira G. P. Zuidgeest(3), Iris Goetz(3), Giovanni B. Frisoni(3), Jenny C. Roberts(3)