Jean‐Paul Mornon

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

48h-index8.5kcitations181works2.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Protein Structure and Dynamics(35), Enzyme Structure and Function(30), Cystic Fibrosis Research Advances(19), Glycosylation and Glycoproteins Research(17), Estrogen and related hormone effects(14)

Publications181 total

Hydrophobic cluster analysis at protein and proteome scales
Biochimie·2025· 1 citedOpen Access
Novel gain-of-function mutants identify a critical region within CFTR membrane-spanning domain 2 controlling cAMP-dependent and ATP-independent channel activation
Cellular and Molecular Life Sciences·2024· 3 citedOpen Access
Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants
International Journal of Molecular Sciences·2022· 6 citedOpen Access
Digging into the 3D Structure Predictions of AlphaFold2 with Low Confidence: Disorder and Beyond
Biomolecules·2022· 37 citedOpen Access
Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR
Cellular and Molecular Life Sciences·2021· 55 citedOpen Access
Author Correction: New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation
Scientific Reports·2021· 1 citedOpen Access
CFTR corrector efficacy is associated with occupancy of distinct binding sites
2021· 1 citedOpen Access
New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation
Scientific Reports·2021· 11 citedOpen Access
WS05.1 AVX-770 binding site within CFTR membrane spanning domain 2 enables ATP-independent channel activation
Journal of Cystic Fibrosis·2020Open Access
Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R
Frontiers in Pharmacology·2020· 8 citedOpen Access
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity
European Journal of Medicinal Chemistry·2020· 13 citedOpen Access
A topology-based investigation of protein interaction sites using Hydrophobic Cluster Analysis
Biochimie·2019· 16 citedOpen Access
P019 Advanced molecular dynamics simulations for understanding the functions and dysfunctions of the CFTR channel
Journal of Cystic Fibrosis·2018Open Access
Combining theoretical and experimental data to decipher CFTR 3D structures and functions
Cellular and Molecular Life Sciences·2018· 33 citedOpen Access
Two Approaches to Structure-Activity Relationships in the Field of Sex-Steroids and Their Analogs
2018
<i>Cis</i>variants identified in F508del complex alleles modulate CFTR channel rescue by small molecules
Human Mutation·2017· 36 cited
WS09.1 3D structures of the full length CFTR protein: combining theoretical and experimental data
Journal of Cystic Fibrosis·2017
The implications of CFTR structural studies for cystic fibrosis drug development
Current Opinion in Pharmacology·2017· 15 cited
Molecular modelling and molecular dynamics of CFTR
Cellular and Molecular Life Sciences·2016· 39 citedOpen Access
The respective roles of polar/nonpolar binary patterns and amino acid composition in protein regular secondary structures explored exhaustively using hydrophobic cluster analysis
Proteins Structure Function and Bioinformatics·2016· 13 citedOpen Access
page 1 of 10Next →

Frequent Co-authors

Isabelle Callebaut(21), Bernard Henrissat(4), Pierre Lehn(4), Jacques Chomilier(4), V. Bissery(3), Anne Poupon(3), Gilles Labesse(3), Patrick M. Dansette(3), D. Ginderow(3), Daniel Mansuy(3), Jean‐François Sadoc(3), N. Colloc’h(3), Christine Gaboriaud(2), T. Benchetrit(2), Sylvie Fabrega(2), P Lehn(2), Isabelle Vigon(2), D. Halaby(2), Siden Top(2), Anne Vessières(2)