Cun-Yu Wang

University of California, Los Angeles — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

45h-index25.5kcitations53works0.02yr avg
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Research Topics

NF-κB Signaling Pathways(13), Cell death mechanisms and regulation(9), Wnt/β-catenin signaling in development and cancer(8), Immune Response and Inflammation(7), Hippo pathway signaling and YAP/TAZ(7)

Publications52 total

Retraction: A Glycolytic Mechanism Regulating an Angiogenic Switch in Prostate Cancer
Cancer Research·2021· 2 citedOpen Access
RAP2 mediates mechanoresponses of the Hippo pathway
Nature·2018· 368 citedOpen Access
Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways
Oncogenesis·2018· 30 citedOpen Access
Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts
Scientific Reports·2016· 38 citedOpen Access
Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell Carcinoma
Scientific Reports·2015· 54 citedOpen Access
Alternative Wnt Signaling Activates YAP/TAZ
Cell·2015· 721 citedOpen Access
Single Amino Acid Change in STING Leads to Constitutive Active Signaling
PLoS ONE·2015· 27 citedOpen Access
Kaposi's Sarcoma-Associated Herpesvirus ORF18 and ORF30 Are Essential for Late Gene Expression during Lytic Replication
Journal of Virology·2014· 46 citedOpen Access
ERG Is a Critical Regulator of Wnt/LEF1 Signaling in Prostate Cancer
Cancer Research·2013· 92 citedOpen Access
The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts
BMC Microbiology·2013· 35 citedOpen Access
Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-κB Signal Transduction Cascade and Immuno-Inflammatory Response in Human Gingival Fibroblasts
PLoS ONE·2013· 182 citedOpen Access
Signaling between Transforming Growth Factor β (TGF-β) and Transcription Factor SNAI2 Represses Expression of MicroRNA miR-203 to Promote Epithelial-Mesenchymal Transition and Tumor Metastasis
Journal of Biological Chemistry·2013· 161 citedOpen Access
The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine
Nature Medicine·2013· 1.2k citedOpen Access
<i>Porphyromonas gingivalis</i> LPS stimulates the expression of LPS-binding protein in human oral keratinocytes <i>in vitro</i>
Innate Immunity·2012· 38 cited
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
Genes & Development·2012· 774 citedOpen Access
Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity differentially modulates the expression of IL-6 and IL-8 in human gingival fibroblasts
Journal Of Clinical Periodontology·2011· 89 cited
IκB kinase ε and TANK-binding kinase 1 activate AKT by direct phosphorylation
Proceedings of the National Academy of Sciences·2011· 220 cited
PS-341 and Histone Deacetylase Inhibitor Synergistically Induce Apoptosis in Head and Neck Squamous Cell Carcinoma Cells
Molecular Cancer Therapeutics·2010· 33 citedOpen Access
Direct Ubiquitination of β-Catenin by Siah-1 and Regulation by the Exchange Factor TBL1
Journal of Biological Chemistry·2010· 134 citedOpen Access
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
Proceedings of the National Academy of Sciences·2010· 600 citedOpen Access
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Frequent Co-authors

Kun‐Liang Guan(10), Albert S. Baldwin(7), LJ Jin(6), Marty W. Mayo(5), Shaoqiong Chen(5), Jia Chang(4), Laurie K. McCauley(4), Honglai Zhang(4), Thanuja D. Herath(4), Richard P. Darveau(4), Chaminda Jayampath Seneviratne(4), Yu Wang(4), Bin Zhao(3), Jindan Yu(3), Wataru Sonoyama(3), Takayoshi Yamaza(3), Stan Gronthos(3), Denis C. Guttridge(3), Eric Tang(3), Qinghua Zeng(3)