Lisa A. Paige

Research Triangle Park Foundation — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index2.0kcitations15works0.02yr avg
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Research Topics

Estrogen and related hormone effects(5), Protein Kinase Regulation and GTPase Signaling(3), Enzyme Structure and Function(3), Protein Structure and Dynamics(2), Microfluidic and Capillary Electrophoresis Applications(2)

Publications15 total

A preliminary metabolomic analysis of older adults with and without depression
International Journal of Geriatric Psychiatry·2006· 140 cited
Activation of the IκB Kinase Complex and Nuclear Factor-κB Contributes to Mutant Huntingtin Neurotoxicity
Journal of Neuroscience·2004· 220 citedOpen Access
Application of the Cytosensor™ Microphysiometer to Drug Discovery
Receptors and Channels·2003
Application of the Cytosensor™ Microphysiometer to Drug Discovery
Receptors and Channels·2003· 8 cited
Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β
Molecular and Cellular Biology·1999· 364 citedOpen Access
Comparative Analyses of Mechanistic Differences Among Antiestrogens1
Endocrinology·1999· 245 citedOpen Access
Peptide Antagonists of the Human Estrogen Receptor
Science·1999· 377 cited
Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β
Proceedings of the National Academy of Sciences·1999· 412 citedOpen Access
Synthesis and biological activity of DNA damaging agents that form decoy binding sites for the estrogen receptor
Proceedings of the National Academy of Sciences·1996· 42 citedOpen Access
Synthesis of Myristoyl CoA Analogues and Myristoyl Peptides as Inhibitors of Myristoyl CoA:Protein /V-Myristoyltransferase
Journal of Pharmaceutical Sciences·1994· 16 cited
A general method for preparation of peptides biotinylated at the carboxy terminus
Analytical Biochemistry·1992· 4 cited
Protein N-myristoylation: Novel target for antitumor and antiviral agents. Characterization of analogs of myristoyl-CoA as inhibitors of myristoyl-CoA:protein N-myristoyltransferase
Purdue e-Pubs (Purdue University System)·1991
Metabolic activation of 2-substituted derivatives of myristic acid to form potent inhibitors of myristoyl CoA:protein N-myristoyltransferase
Biochemistry·1990· 88 cited
Detection of myristoyl CoA:protein N-myristoyltransferase activity by ion-exchange chromatography
Analytical Biochemistry·1989· 11 cited
S-(2-oxopentadecyl)-CoA, a nonhydrolyzable analog of myristoyl-CoA, is a potent inhibitor of myristoyl-CoA: protein N-myristoyltransferase
Journal of Medicinal Chemistry·1989· 57 cited

Frequent Co-authors

Robert L. Geahlen(5), John D. Norris(4), Donald P. McDonnell(4), Dana M. Fowlkes(4), John M. Cassady(4), Dale J. Christensen(3), Ching‐yi Chang(3), Paul T. Hamilton(3), Hanne Grøn(2), Guo Qiang Zheng(2), Shawn DeFrees(2), Kirsten Wille(2), Alan J. Higgins(2), Elizabeth B. Gottlin(1), Karen Padilla(1), Lawrence M. Ballas(1), Maria R. Huacani(1), Daju Fan(1), Daniel J. Kenan(1), Ashini L. Wijayaratne(1)