Neil W. Isaacs

University of Glasgow — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

51h-index11.7kcitations219works0.02yr avg
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Research Topics

Photosynthetic Processes and Mechanisms(46), Enzyme Structure and Function(32), Glycosylation and Glycoproteins Research(20), Protein Structure and Dynamics(19), Algal biology and biofuel production(16)

Publications219 total

A history of experimental phasing in macromolecular crystallography
Acta Crystallographica Section D Structural Biology·2016· 7 citedOpen Access
Multiple roles for the C-terminal tail of the chemokine scavenger D6.
Journal of Biological Chemistry·2013Open Access
Crystal structure of a <i>Trypanosoma brucei</i> metacaspase
Proceedings of the National Academy of Sciences·2012· 84 citedOpen Access
Save our helium
The New Scientist·2012
THE STRUCTURE OF METACASPASE 2 FROM T. BRUCEI DETERMINED IN THE PRESENCE OF CALCIUM CHLORIDE
2012
The structure of metacaspase 2 from T. brucei determined in the presence of Samarium
2012
THE STRUCTURE OF METACASPASE 2 (C213A MUTANT) FROM T. BRUCEI
2012
The structural basis for metacaspase substrate specificity and activation
2012
New insights into the structure of the reaction centre from <i>Blastochloris viridis</i>: evolution in the laboratory
Biochemical Journal·2011· 33 cited
The 2011 Joint Sino–U.K. Protein Symposium
Biochemical Society Transactions·2011
Outer Membrane Protein A of Bovine and Ovine Isolates of Mannheimia haemolytica Is Surface Exposed and Contains Host Species-Specific Epitopes
Infection and Immunity·2011· 26 citedOpen Access
Crystal Structure of the Reaction Centre from Blastochloris viridis strain DSM 133 (ATCC 19567) substrain-94
2011
Mapping lipid and detergent molecules at the surface of membrane proteins
Biochemical Society Transactions·2011· 5 cited
The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory
Acta Crystallographica Section D Biological Crystallography·2011· 18 citedOpen Access
Autotransporter passenger domain secretion requires a hydrophobic cavity at the extracellular entrance of the β-domain pore
Biochemical Journal·2011· 45 cited
High-throughput identification of purification conditions leads to preliminary crystallization conditions for three inner membrane proteins
Molecular Membrane Biology·2011· 7 cited
Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from<i>Yersinia pseudotuberculosis</i>
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2010· 7 citedOpen Access
Crystal Structure of Leishmania major Oligopeptidase B Gives Insight into the Enzymatic Properties of a Trypanosomatid Virulence Factor
Journal of Biological Chemistry·2010· 65 citedOpen Access
Expression, purification, crystallization and preliminary X-ray crystallographic data from TktA, a transketolase from the lactic acid bacterium<i>Lactobacillus salivarius</i>
Acta Crystallographica Section F Structural Biology and Crystallization Communications·2010· 1 cited
Structure of Oligopeptidase B from Leishmania major
2010
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Frequent Co-authors

Richard J. Cogdell(23), Stephen M. Prince(14), Miroslav Z. Papiz(7), Tina Howard(7), Andrew A. Freer(6), A.W. Roszak(6), Alastair T. Gardiner(6), Paul K. Fyfe(6), Fujiang Zhu(6), Lutz Hecht(6), Laurence D. Barron(6), Karen McLuskey(5), A. M. Hawthornthwaite-Lawless(4), Andy Freer(4), Michael R. Jones(4), G.E. Tranter(4), June Southall(3), Christopher J. Law(3), Paul Emsley(3), Neil F. Fairweather(3)